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20454 St3gal5

20454

St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

protein-coding

Mus musculus

基因描述

Type Description
Definition ST3 beta-galactoside alpha-2,3-sialyltransferase 5

研究结论

Date Results Publications
2021-01-09 13:32:00 Tumor hypoxia regulates ganglioside GM3 synthase, which contributes to oxidative stress resistance in malignant melanoma. 32861756
2019-06-15 10:04:00 HEK-293T clones permanently expressing HaloTag-ST3GAL5 carrying each of the five variants were assessed by quantitative PCR, flow cytometry, western blotting and confocal microscopy. Compared with the very mild phenotype of st3gal5 KO mouse models, the results suggest that unknown mechanisms, in addition to the lack of a-b-c-series gangliosides, contribute to the syndrome. 30576498
2018-06-30 11:54:00 A new liver-specific c-type mRNA transcriptional variant of mouse ST3GAL5 protein has been identified. 28808804
2018-01-06 10:57:00 We used GM2/GD2 synthase (B4galnt1)-deficient mice to immunize by liposomes embedded with GD1alpha or acidic glycolipid fractions from brain of St3gal5-deficient mice. Specificities of established mAbs as analyzed by enzyme-linked immunosorbent assay and thin-layer chromatography-immunostaining were very high among various gangliosides. 27102283
2017-10-21 13:13:00 These studies establish ganglioside GM3 as a new candidate responsible for neuropathic pain and small fiber neuropathy in diabetes. 27590073

名称对应

Type IDs
Synonymous 3S-T, Siat9, [a]2
Gene
UniProtKB-ID: SIAT9_MOUSE, A0A0R4J1J3_MOUSE
UniprotKB: O88829, A0A0R4J1J3
UniParc: UPI000173AA38, UPI00001512DE, UPI0000023355
EMBL: BC138559, Y18022, Y15003, AB018048, Y18023, AK165726, AF119416, BC138557, AK012961, AC127244, AK159000, AB013302
Ensembl: ENSMUSG00000056091
KO: mmu:20454
Nucleutide sequences
EMBL-CDS: BAE38355.1, AAF66147.1, AAI38560.1, AAI38558.1, BAA33491.1, BAE34763.1, CAA75236.1, CAC79655.1, CAA75235.1, BAA76467.1, BAB28571.1, CAC79654.1
Ensembl_TRS: ENSMUST00000069994, ENSMUST00000114112
Protein sequencees
Ensembl_PRO: ENSMUSP00000070414, ENSMUSP00000109747
RefSeq: XP_006505880.1, XP_006505881.1, XP_006505883.1, XP_017176962.1, XP_006505882.1, XP_036021875.1, NP_001030305.1, XP_006505879.1, NP_035505.2
Others
UniRef100: UniRef100_O88829, UniRef100_A0A0R4J1J3
UniRef90: UniRef90_O88829
UniRef50: UniRef50_Q9UNP4
UniGene: Mm.38248
CCDS: CCDS20237.1

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