| Type | Description |
|---|---|
| Definition | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| Date | Results | Publications |
|---|---|---|
| 2016-12-24 11:38:00 | Mice deficient for ST8SiaIV have impaired long-term spatial memory in two tasks that critically rely on the hippocampus. | 25596866 |
| 2016-12-17 11:37:00 | Results demonstrate that the early development of calbindin-positive periglomerular interneurons depends on the presentation of polysialic acid on NCAM and requires the activity of both St8sia2 and St8sia4 | 26153130 |
| 2016-04-16 10:49:00 | NCAM-140 significantly promoted cell proliferation, motility and migration, while polysialylation of NCAM-140 catalyzed by STX, but not by PST, enhanced NCAM-mediated cell migration, but not cell proliferation or motility. | 25885924 |
| 2013-11-02 11:04:00 | ST8SiaIV synthesized polySia selectively on a NRP2 glycoform that was characterized by the presence of sialylated core 1 and core 2 O-glycans. | 23801331 |
| 2013-05-04 11:43:00 | Results indicate that the polySTs ST8SiaII and ST8SiaIV not only recognize an acidic patch in the FN1 domain of NCAM but also must contact sequences in the Ig5 domain for polysialylation of Ig5 N-glycans to occur. | 23341449 |
| Type | IDs |
|---|---|
| Synonymous | PST, PST-1, SIAT8-D, ST8SiaIV, Siat8d |
| Gene |
UniProtKB-ID:
SIA8D_MOUSE,
Q6PAS1_MOUSE,
A0A087WRA0_MOUSE,
Q53WR7_MOUSE
UniprotKB:
Q64692,
Q6PAS1,
A0A087WRA0,
Q53WR7
UniParc:
UPI000052CAD7,
UPI0000000712,
UPI00001D9542
EMBL:
Y09485,
AC102483,
AC174160,
Y09487,
AC104893,
AJ223956,
Y09484,
Y09486,
BC060112,
X86000,
Y09488
Ensembl:
ENSMUSG00000040710
KO:
mmu:20452
|
| Nucleutide sequences |
EMBL-CDS:
CAA59992.1,
AAH60112.1,
CAA11685.1,
CAA70692.1
Ensembl_TRS:
ENSMUST00000043336,
ENSMUST00000189556
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000043477,
ENSMUSP00000140534
RefSeq:
XP_036018821.1,
XP_036018814.1,
XP_036018816.1,
NP_001153217.1,
NP_033209.1,
XP_006529338.1
|
| Others |
UniRef100:
UniRef100_Q64692,
UniRef100_Q6PAS1
UniRef90:
UniRef90_Q6PAS1,
UniRef90_Q92187
UniRef50:
UniRef50_Q6KC03,
UniRef50_Q92187
UniGene:
Mm.306228
CCDS:
CCDS15201.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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