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20450 St8sia2

20450

St8sia2

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

protein-coding

Mus musculus

基因描述

Type Description
Definition ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

研究结论

Date Results Publications
2020-10-31 13:18:00 Effect of expression alteration in flanking genes on phenotypes of St8sia2-deficient mice. 31541165
2020-07-04 11:14:00 the data demonstrate a cell-autonomous impact of ST8SIA2 on cortical interneuron migration and the distribution of parvalbumin-positive interneurons in the anterior cortex 31608978
2016-12-17 11:37:00 Results demonstrate that the early development of calbindin-positive periglomerular interneurons depends on the presentation of polysialic acid on NCAM and requires the activity of both St8sia2 and St8sia4 26153130
2016-04-16 10:49:00 NCAM-140 significantly promoted cell proliferation, motility and migration, while polysialylation of NCAM-140 catalyzed by STX enhanced NCAM-mediated cell migration, but not cell proliferation or motility. 25885924
2015-08-29 10:42:00 These results reveal that reduced polysialylation in St8sia2 (-/-) mice leads to pathological brain development and schizophrenia-like behavior. 24057454

名称对应

Type IDs
Synonymous AI323367, ST8SiaII, STX, Siat8b
Gene
UniProtKB-ID: SIA8B_MOUSE
UniprotKB: O35696
UniParc: UPI00000226EB
EMBL: X99649, X99651, X99647, X99648, BC096546, X83562, CH466543, X99646, X99650
Ensembl: ENSMUSG00000025789
KO: mmu:20450
Nucleutide sequences
EMBL-CDS: CAA58548.1, EDL07123.1, CAA67965.1, AAH96546.1
Ensembl_TRS: ENSMUST00000026896
Protein sequencees
Ensembl_PRO: ENSMUSP00000026896
RefSeq: NP_033207.2, XP_006540794.1
Others
UniRef100: UniRef100_O35696
UniRef90: UniRef90_Q07977
UniRef50: UniRef50_Q07977
UniGene: Mm.4954
CCDS: CCDS21365.1

全选

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研究热度

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