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20444 St3gal2

20444

St3gal2

ST3 beta-galactoside alpha-2,3-sialyltransferase 2

protein-coding

Mus musculus

基因描述

Type Description
Definition ST3 beta-galactoside alpha-2,3-sialyltransferase 2

研究结论

Date Results Publications
2020-11-21 13:30:00 GT1b functions as a novel endogenous agonist of toll-like receptor 2 inducing neuropathic pain. 32030804
2018-01-06 10:47:00 t3gal2-null mice display a reduced respiratory exchange ratio compared to WT mice, indicating a preference for lipid oxidation as an energy source. Despite their altered metabolism, St3gal2-null mice were hyperactive. We conclude that altered ganglioside expression in adipose tissue results in diminished IR sensitivity and late-onset obesity. 27683310
2015-09-26 19:08:00 St3gal2/3 double-null mice displayed dysmyelination marked by a reduction in major myelin proteins, fewer myelinated axons, a decrease in myelin thickness, possibly by dysregulation of ganglioside-mediated oligodendroglial precursor cell proliferation. 25846372
2012-05-05 10:50:00 An adult onset cardiac dilatation in a transgenic mouse line with Galbeta1,3GalNAc alpha2,3-sialyltransferase II (ST3Gal-II) transgenes, is reported. 21986317
2010-01-21 00:00:00 was not found to play a role in regulating synthesis of selectin ligands nor in vitro rolling of marrow-derived neutrophils on E- or P-selectins presented by Chinese hamster ovary cells 12393657

名称对应

Type IDs
Synonymous AI429591, AW822065, ST3GalII, Siat5
Gene
UniProtKB-ID: SIA4B_MOUSE
UniprotKB: Q11204
UniParc: UPI0000023881
EMBL: AK053827, CH466525, X76989, BC066064, AK131653
Ensembl: ENSMUSG00000031749
KO: mmu:20444
Nucleutide sequences
EMBL-CDS: AAH66064.1, EDL11478.1, BAE20742.1, CAA54294.1, BAC35543.1
Ensembl_TRS: ENSMUST00000034197
Protein sequencees
Ensembl_PRO: ENSMUSP00000034197
RefSeq: XP_006530850.1, XP_006530849.1, XP_017168113.1, XP_006530851.1, XP_036009743.1, NP_033205.2
Others
UniRef100: UniRef100_Q11204
UniRef90: UniRef90_Q11204
UniRef50: UniRef50_Q16842
UniGene: Mm.200388
CCDS: CCDS22667.1

全选

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