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20425 Shmt1

20425

Shmt1

serine hydroxymethyltransferase 1 (soluble)

protein-coding

Mus musculus

基因描述

Type Description
Definition serine hydroxymethyltransferase 1 (soluble)

研究结论

Date Results Publications
2013-08-31 10:39:00 Shmt1 and dietary folate deficiency influence metabolic markers of homocysteine remethylation in mice. 23700346
2012-02-25 11:27:00 SHMT1 and TYMS localization to the nucleus is essential to prevent uracil accumulation in DNA 22057276
2011-07-30 10:37:00 Data show that Shmt1 hemizygosity was associated with increased risk for intestinal cancer in Apc(min)(/+) mice through a gene-by-diet interaction. 21406397
2011-05-28 11:00:00 These results provide evidence that disruption of Shmt1 expression causes NTDs by impairing thymidylate biosynthesis and shows that changes in the expression of genes that encode folate-dependent enzymes may be key determinates of NTD risk. 21346092
2011-03-12 10:28:00 It is one of the genetic components regulating PPI in mice and is relevant to schizophrenia susceptibility in humans. (review) 21226315

名称对应

Type IDs
Synonymous AI324848, AI385541, C81125, Shmt, mshmt, mshmt1, mshmt2
Gene
UniProtKB-ID: GLYC_MOUSE
UniprotKB: P50431
UniParc: UPI0000021609
EMBL: AL596215, X94479, X94478, BC026055, AF237702
Ensembl: ENSMUSG00000020534
KO: mmu:20425
Nucleutide sequences
EMBL-CDS: AAK15040.1, CAA64226.1, CAA64225.1, AAH26055.1
Ensembl_TRS: ENSMUST00000018744
Protein sequencees
Ensembl_PRO: ENSMUSP00000018744
RefSeq: XP_006532707.1, NP_033197.2
Others
UniRef100: UniRef100_P50431
UniRef90: UniRef90_P34896
UniRef50: UniRef50_P34896
UniGene: Mm.364956
CCDS: CCDS24799.1

全选

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研究热度

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