| Type | Description |
|---|---|
| Definition | ceramide synthase 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:25:00 | Activation of SIRT1 Enhances Epidermal Permeability Barrier Formation through Ceramide Synthase 2- and 3-Dependent Mechanisms. | 31958434 |
| 2018-02-03 11:02:00 | Novel mutations in CERS3 co-segregated with the ichthyosis phenotype in six Iranian families. | 28875980 |
| 2016-08-20 10:23:00 | These results suggest that the phosphorylation of ceramide synthases may be a key regulatory point in the control of the distribution and levels of sphingolipids of various acyl-chain lengths. | 26887952 |
| 2016-05-14 11:05:00 | testis-specific SLs, which we also link to CerS3 in human testis, are quintessential for male fertility. | 26045466 |
| 2013-11-02 11:43:00 | Our findings demonstrate that synthesis of very long chain ceramides by CerS3 is a crucial early step for the skin barrier formation and link disorders presenting with congenital ichthyosis to defects in sphingolipid metabolism and lipid architecture. | 23549421 |
| Type | IDs |
|---|---|
| Synonymous | ARCI9, LASS3 |
| Gene |
UniProtKB-ID:
CERS3_HUMAN
UniprotKB:
Q8IU89
UniParc:
UPI00001975AB
EMBL:
AC027020,
BC034500,
BC028703,
BC034970,
AC015723
Ensembl:
ENSG00000154227
KO:
hsa:204219
|
| Nucleutide sequences |
EMBL-CDS:
AAH34970.1,
AAH34500.1,
AAH28703.1
Ensembl_TRS:
ENST00000394113,
ENST00000538112,
ENST00000284382
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000377672,
ENSP00000437640,
ENSP00000284382
RefSeq:
NP_001277272.1,
XP_016877491.1,
XP_011519659.1,
NP_849164.2,
NP_001277270.1,
NP_001365718.1,
XP_016877493.1,
NP_001277271.1,
XP_011519660.1,
XP_011519657.1,
XP_016877492.1
|
| Others |
UniRef100:
UniRef100_Q8IU89
UniRef90:
UniRef90_Q8IU89
UniRef50:
UniRef50_Q8IU89
UniGene:
Hs.662371
CCDS:
CCDS10384.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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