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20411 Sorbs1

20411

Sorbs1

sorbin and SH3 domain containing 1

protein-coding

Mus musculus

基因描述

Type Description
Definition sorbin and SH3 domain containing 1

研究结论

Date Results Publications
2019-10-26 11:28:00 These observations reveal a critical role of vinexin alpha and CAP in mechanotransduction and MSC differentiation. 30068914
2017-11-25 15:14:00 The first SNP rs29972765 is located in a gene desert on chromosome 18, about 72 kb upstream of Skor2 . The second SNP rs30415957 resides in the intron of Plce1.The remaining two SNPs (rs30768258 and rs31216810) are close to each other on chromosome 19, in the vicinity of Sorbs1. Knockdown of Sorbs1 by siRNA attenuates the induction of differentiation marker gene Prl8a2 27449513
2016-05-21 12:47:00 The study screened CrkL binding proteins using RNA interference and identified Sorbs1 and Sorbs2 as two proteins that are enriched at AChR clusters and are required for the formation of AChR aggregation in vitro. 26527617
2014-11-08 10:52:00 Suggest a novel modulatory role for CAP in the heart as a key protein stabilizing antiviral type I interferon production, while protecting from excessive cytotoxic responses in CVB3 mediated endocarditis. 24763933
2013-05-18 12:08:00 Low- and high-dose ursolic acid can improve the glycometabolism and differentiation of 3T3-L1 adipocytes with insulin resistance by up-regulating the expression of CAP. 22883405

名称对应

Type IDs
Synonymous 2310065E01Rik, 9530001P15Rik, CAP, SH3P12, Sh3d5, mKIAA1296
Gene
UniProtKB-ID: SRBS1_MOUSE, A0A286YDN0_MOUSE, A0A286YCQ0_MOUSE, E9Q6A3_MOUSE, E9PYX6_MOUSE, D3Z5J3_MOUSE, E9QNA7_MOUSE
UniprotKB: Q62417, A0A286YDN0, A0A286YCQ0, E9Q6A3, E9PYX6, D3Z5J3, E9QNA7
UniParc: UPI00005D3885, UPI000042971E, UPI0003D6DF3D, UPI00001EC52B, UPI00004032E1, UPI00004032E0, UPI0000029014, UPI00000E7B28, UPI0000029610, UPI00004032D1, UPI000002960F, UPI0000565D29, UPI00005D3886
EMBL: AC144949, AC170187, AK122487, BC012703, AF078667, AC142101, U58883, AF521593, AF078666, AK035212
Ensembl: ENSMUSG00000025006
KO: mmu:20411
Nucleutide sequences
EMBL-CDS: AAC71776.1, BAC65769.2, AAD16008.1, BAC28980.1, AAH12703.1, AAD16007.1, AAM77354.1
Ensembl_TRS: ENSMUST00000226047, ENSMUST00000224247, ENSMUST00000225148, ENSMUST00000225786, ENSMUST00000165469, ENSMUST00000165212, ENSMUST00000225153, ENSMUST00000099467, ENSMUST00000099466
Protein sequencees
Ensembl_PRO: ENSMUSP00000153489, ENSMUSP00000153097, ENSMUSP00000152957, ENSMUSP00000153336, ENSMUSP00000125768, ENSMUSP00000126460, ENSMUSP00000153313, ENSMUSP00000097066, ENSMUSP00000097065
RefSeq: XP_030106676.1, NP_001030135.1, XP_036017379.1, XP_036017375.1, XP_017173584.1, XP_017173586.1, XP_036017384.1, NP_033192.2, XP_036017372.1, XP_011245485.1, XP_011245474.1, XP_030106677.1, XP_011245482.1, XP_030106679.1, XP_030106685.1, XP_017173585.1, XP_011245495.1, XP_017173582.1, XP_036017373.1, XP_011245500.1, XP_036017365.1, XP_036017378.1, NP_001030136.1, XP_036017369.1, XP_011245475.1, XP_030106672.1, XP_011245493.1, XP_036017376.1, XP_036017382.1, XP_030106673.1, XP_036017370.1, XP_006526873.1, XP_030106681.1, NP_848139.1, XP_006526876.1, XP_036017367.1, XP_030106680.1, XP_036017368.1, XP_017173579.1, XP_036017377.1, XP_011245477.1, XP_011245501.1, XP_036017380.1, XP_036017364.1, NP_001030134.1, XP_030106675.1, XP_036017383.1, XP_036017381.1, XP_036017371.1, XP_030106664.1, XP_036017366.1, XP_030106674.1, XP_011245492.1, XP_030106668.1, XP_030106687.1
Others
UniRef100: UniRef100_D3Z5J3, UniRef100_E9Q6A3, UniRef100_A0A286YCQ0, UniRef100_E9PYX6, UniRef100_A0A286YDN0, UniRef100_E9QNA7, UniRef100_Q62417
UniRef90: UniRef90_E9Q6A3, UniRef90_E9QNA7, UniRef90_E9PYX6, UniRef90_A0A286YDN0, UniRef90_A0A286YCQ0, UniRef90_Q62417, UniRef90_D3Z5J3
UniRef50: UniRef50_Q62417-7, UniRef50_Q62417-6, UniRef50_Q9BX66-10, UniRef50_Q62417-2, UniRef50_Q62417, UniRef50_Q62417-3
UniGene: Mm.210815, Mm.440351, Mm.489013
CCDS: CCDS37979.1, CCDS37978.1, CCDS89388.1, CCDS37981.1

全选

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