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20410 Sorbs3

20410

Sorbs3

sorbin and SH3 domain containing 3

protein-coding

Mus musculus

基因描述

Type Description
Definition sorbin and SH3 domain containing 3

研究结论

Date Results Publications
2020-02-15 11:55:00 these results demonstrate that the H2 helix in vinexin alpha plays a critical role in ECM stiffness-dependent regulation of vinculin and cell behaviors. 30578314
2019-10-26 11:28:00 These observations reveal a critical role of vinexin alpha and CAP in mechanotransduction and MSC differentiation. 30068914
2018-06-09 11:41:00 Differential roles of SORBS proteins in mechanotransduction. 28864765
2018-02-24 10:17:00 Vinexin beta deficiency attenuates atherogenesis primarily by suppressing vascular inflammation and inactivating Akt-nuclear factor kappaB signaling. Our data suggest that vinexin beta could be a therapeutic target for the treatment of atherosclerosis. 28209562
2017-07-08 10:09:00 The results indicate that lipid rafts play an important role in extracellular matrix stiffness regulation of cell migration via expression vinculin and its interaction with vinexin alpha. 28485208

名称对应

Type IDs
Synonymous SCAM-1, SH3P3, Sh3d4, vinexin-g
Gene
UniProtKB-ID: VINEX_MOUSE, Q8K0M3_MOUSE
UniprotKB: Q9R1Z8, Q8K0M3
UniParc: UPI00000E5BD0, UPI0000021DE7
EMBL: AC151836, AF064806, BC030933, AB190911, U58889
Ensembl: ENSMUSG00000022091
KO: mmu:20410
Nucleutide sequences
EMBL-CDS: AAC52642.1, AAD32303.1, AAH30933.1, BAD91315.1
Ensembl_TRS: ENSMUST00000022682, ENSMUST00000227653, ENSMUST00000227259
Protein sequencees
Ensembl_PRO: ENSMUSP00000022682, ENSMUSP00000153715, ENSMUSP00000154195
RefSeq: XP_006518805.1, XP_006518800.1, NP_001258338.1, XP_006518799.1, NP_001258336.1, XP_030103560.1, NP_035496.1, XP_006518806.1, XP_006518804.1, NP_001258337.1, XP_030103559.1, XP_030103561.1
Others
UniRef100: UniRef100_Q9R1Z8
UniRef90: UniRef90_Q9R1Z8
UniRef50: UniRef50_O60504
UniGene: Mm.5068
CCDS: CCDS27249.1

全选

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