| Type | Description |
|---|---|
| Definition | SH3-domain GRB2-like 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:55:00 | Endophilin A2 deficiency protects rodents from autoimmune arthritis by modulating T cell activation. | 33504785 |
| 2019-06-22 11:13:00 | Endophilin-A2 is a critical mediator of endothelial cell migration and sprouting angiogenesis. ENDOA2 deficiency reduces VEGFR2 internalization and inhibits downstream activation of the signaling effector PAK but not ERK, thereby affecting front-rear polarity and migration but not proliferation or survival. | 31138815 |
| 2017-02-25 12:22:00 | This study provides a new mechanism by which endophilin A2 regulates ClC-3 channel activity, and sheds light on how ClC-3 is transported to cell membranes to play its critical role as a chloride channel in VSMCs function | 27760895 |
| 2013-03-30 12:17:00 | Mutation in the FAK gene disrupted the function of FAK scaffolding to mediate endophilin A2 phosphorylation at Tyr-315 by Src, leading to the decreased surface expression of MT1-MMP. | 23255596 |
| 2010-12-04 10:56:00 | these results demonstrate that MNSFbeta/endophilin II inhibits the signal pathway upstream of IKK activation, but not downstream of TLR2 signaling. | 20849826 |
| Type | IDs |
|---|---|
| Synonymous | C77078, EEN, SH3P8, Sh3d2b |
| Gene |
UniProtKB-ID:
SH3G1_MOUSE,
Q3TRJ7_MOUSE,
A0A3B2W7K0_MOUSE
UniprotKB:
Q62419,
Q3TRJ7,
A0A3B2W7K0
UniParc:
UPI0002357A6D,
UPI0000029018
EMBL:
U58885,
AK162715,
BC138603,
BC138602,
CT009719
Ensembl:
ENSMUSG00000003200
KO:
mmu:20405
|
| Nucleutide sequences |
EMBL-CDS:
AAC71775.1,
AAI38603.1,
BAE37032.1,
AAI38604.1
Ensembl_TRS:
ENSMUST00000003268,
ENSMUST00000233803
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000003268,
ENSMUSP00000156570
RefSeq:
NP_001239400.1,
NP_001344578.1,
NP_038692.1
|
| Others |
UniRef100:
UniRef100_A0A3B2W7K0,
UniRef100_Q62419
UniRef90:
UniRef90_A0A3P4M139,
UniRef90_Q62419
UniRef50:
UniRef50_Q99961-3,
UniRef50_A0A091PK98
UniGene:
Mm.1773
CCDS:
CCDS28891.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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