| Type | Description |
|---|---|
| Definition | serine/arginine-rich splicing factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:06:00 | prevention of SRSF3 degradation in vivo partially protected mice from hepatic steatosis, fibrosis and inflammation. | 31393851 |
| 2020-05-30 12:34:00 | This study showed that reduced SRSF3 expression could promote cellular senescence through its APA-dependent function, largely extending our mechanistic understanding in splicing factor regulated cellular senescence. | 30835716 |
| 2020-04-25 12:21:00 | Cardiomyocyte-specific loss of SRSF3 expression results in decapping of critical mRNAs involved in cardiac contraction and systolic dysfunction. | 31145021 |
| 2019-05-18 10:46:00 | SRSF3 binds to the core pluripotency transcription factor Nanog mRNA to facilitate its nucleo-cytoplasmic export independent of splicing. In the absence of SRSF3 binding, Nanog mRNA is sequestered in the nucleus and protein levels are severely downregulated. | 29741478 |
| 2018-12-22 11:16:00 | Study identified a novel splicing network composed of RBM4a, SRSF3, and MAP4K4 in brown adipogenesis and subsequently manipulating the effect of downstream JNK signaling which contributes to insulin resistance and reduced metabolism. | 30200638 |
| Type | IDs |
|---|---|
| Synonymous | AL024116, Sfrs3, X16 |
| Gene |
UniProtKB-ID:
SRSF3_MOUSE
UniprotKB:
P84104
UniParc:
UPI0000004131,
UPI000002B379
EMBL:
AK011657,
AK146010,
X91656,
AK145089,
AK150912,
AK078891,
AK153209,
X53824,
BC071196,
AK135298,
BC083316,
AK134177,
AK145715,
BC068111,
AK146253
Ensembl:
ENSMUSG00000071172
KO:
mmu:20383
|
| Nucleutide sequences |
EMBL-CDS:
BAE27015.1,
BAE22040.1,
AAH68111.1,
BAE26230.1,
BAC37445.1,
AAH83316.1,
BAE26606.1,
BAE26830.1,
BAE31808.1,
CAA37821.1,
AAH71196.1,
CAA62844.1,
CAA62845.1,
BAE22483.1,
BAB27762.1,
BAE29950.1
Ensembl_TRS:
ENSMUST00000130216,
ENSMUST00000037776
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000117045,
ENSMUSP00000049025
RefSeq:
NP_038691.1
|
| Others |
UniRef100:
UniRef100_P84103
UniRef90:
UniRef90_P84103
UniRef50:
UniRef50_P84103
UniGene:
Mm.6787,
Mm.473125
CCDS:
CCDS28590.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员