| Type | Description |
|---|---|
| Definition | erythrocyte membrane protein band 4.2 |
| Date | Results | Publications |
|---|---|---|
| 2011-01-29 10:36:00 | study shows that cytoplasmic hereditary spherocytosis mutants cause impaired binding of protein 4.2 to AE1, leaving protein 4.2 susceptible to loss during erythrocyte development | 21039340 |
| 2010-05-31 11:05:00 | Data suggest that one or both of proteins 4.1 and 4.2 cause a portion of band 3 to localize near the spectrin-actin junctions and provide another point of attachment between the membrane skeleton and the lipid bilayer. | 20007969 |
| 2010-01-21 00:00:00 | protein 4.2 strongly influences CD47 levels as well as the extent of membrane skeleton attachment in erythrocytes | 14551146 |
| 2010-01-21 00:00:00 | Evidence protein 4.2 interacts with the Rh membrane complex member CD47 obtained from red cells of patients with hereditary spherocytosis associated with complete protein 4.2 deficiency | 12393467 |
| 2010-01-21 00:00:00 | spectrin binding domain | 12049649 |
| Type | IDs |
|---|---|
| Synonymous | PA, SPH5 |
| Gene |
UniProtKB-ID:
EPB42_HUMAN
UniprotKB:
P16452
UniParc:
UPI000050ED3D,
UPI0000551B79,
UPI000013E639
EMBL:
L06513,
L06512,
L06448,
M30647,
M30646,
L06515,
L06449,
CH471125,
BC099627,
AC068724,
M29399,
L06518,
L06516,
L06511,
M60298,
L06450,
L06447,
L06517,
BC096093,
L06519,
BC096094
Ensembl:
ENSG00000166947
KO:
hsa:2038
|
| Nucleutide sequences |
EMBL-CDS:
EAW92591.1,
AAH99627.1,
AAA35798.1,
AAA36402.1,
AAA52385.1,
AAH96094.1,
AAA36401.1,
AAA74589.1,
AAH96093.1
Ensembl_TRS:
ENST00000622454,
ENST00000441366,
ENST00000648595
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000497777,
ENSP00000481226,
ENSP00000396616
RefSeq:
XP_011519652.1,
XP_011519653.1,
XP_011519656.1,
XP_011519655.1,
NP_000110.2,
XP_011519651.1,
XP_005254282.1,
NP_001107606.1,
XP_011519654.1
|
| Others |
UniRef100:
UniRef100_P16452
UniRef90:
UniRef90_P16452
UniRef50:
UniRef50_P16452
UniGene:
Hs.368642
CCDS:
CCDS10093.1,
CCDS45249.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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