| Type | Description |
|---|---|
| Definition | secreted frizzled-related protein 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:33:00 | The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver. | 31336149 |
| 2020-04-04 11:07:00 | these data show autocrine and paracrine effects of Sfrp4 in regulating osteoclast (OC) genesis and demonstrate that the increase in endosteal OCs seen in Sfrp4 (-/-) mice is a consequence of noncanonical Wnt/Ror2/Jnk signaling activation in OCs overriding the negative effect that activation of canonical Wnt/beta-catenin signaling has on OC genesis | 31239337 |
| 2020-01-11 11:52:00 | miR-943-3p accelerated the progression of airway inflammation and remodeling in allergic asthma via suppressing the activity of SFRP4 through Wnt signaling pathway in asthma patients and OVA-induced mice. | 31101982 |
| 2019-12-14 11:29:00 | Knockdown of Sfrp4 in myocardium attenuated myocardial ischemia and reperfusion injury by AKT signaling pathway. | 31113729 |
| 2019-12-07 10:50:00 | Taken together, our results suggest that SFRP4 acts to attenuate granulosa cell responsiveness to gonadotropins, thereby decreasing follicle survival, ovulatory rate, and fertility. | 30942852 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SFRP4_MOUSE
UniprotKB:
Q9Z1N6
UniParc:
UPI0000020CA5
EMBL:
AK080766,
BC034853,
AF364906,
U88569,
AF117709
Ensembl:
ENSMUSG00000021319
KO:
mmu:20379
|
| Nucleutide sequences |
EMBL-CDS:
AAD12306.1,
AAH34853.1,
AAL14904.1,
BAC38013.1
Ensembl_TRS:
ENSMUST00000002883
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000002883
RefSeq:
NP_057896.1
|
| Others |
UniRef100:
UniRef100_Q9Z1N6
UniRef90:
UniRef90_Q9JLS4
UniRef50:
UniRef50_Q9JLS4
UniGene:
Mm.42095
CCDS:
CCDS26261.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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