| Type | Description |
|---|---|
| Definition | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| Date | Results | Publications |
|---|---|---|
| 2020-08-13 17:13:00 | Sema4d role in the regulation of nitric oxide production in the microglia.The enhancement of nitric oxide production by Sema4D is involved in partial Erk1 and Erk2 inhibition and up-regulation of Iinterferon-beta. | 31708102 |
| 2019-12-28 12:05:00 | Sema4D regulates microglial proliferation in part by regulating the competitive balance of l-arginine metabolism. | 30922994 |
| 2019-03-09 12:35:00 | Sema4D induces the clustering of inhibitory presynaptic components via Plexin-B1. | 29981480 |
| 2019-02-09 11:59:00 | These results demonstrate a novel physiological function for sema4D/plxnB1 signaling in retinal pigment epithelium phagocytosis. | 28624895 |
| 2019-01-12 10:52:00 | suggest that STING activates ADAM17 and that this activation produces soluble proinflammatory SEMA4D independently of the TBK1/IRF3-mediated transcriptional pathway | 29618514 |
| Type | IDs |
|---|---|
| Synonymous | CD100, Semacl2, Semaj, Semcl2, coll-4 |
| Gene |
UniProtKB-ID:
SEM4D_MOUSE
UniprotKB:
O09126
UniParc:
UPI0000021BF6
EMBL:
U69535,
CH466546,
BC049780
Ensembl:
ENSMUSG00000021451
KO:
mmu:20354
|
| Nucleutide sequences |
EMBL-CDS:
EDL41105.1,
EDL41107.1,
EDL41106.1,
AAH49780.2,
AAC52964.1
Ensembl_TRS:
ENSMUST00000110039,
ENSMUST00000110040,
ENSMUST00000021900
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000105667,
ENSMUSP00000021900,
ENSMUSP00000105666
RefSeq:
XP_036013839.1,
NP_001365248.1,
XP_036013841.1,
NP_001268809.1,
NP_001365245.1,
XP_036013840.1,
NP_001365250.1,
NP_001365242.1,
NP_038688.2,
NP_001365252.1,
NP_001365244.1,
NP_001365247.1,
NP_001365251.1,
NP_001365253.1,
NP_001365249.1,
NP_001365246.1,
NP_001365243.1,
NP_001365254.1,
XP_036013838.1
|
| Others |
UniRef100:
UniRef100_O09126
UniRef90:
UniRef90_O09126
UniRef50:
UniRef50_Q92854
UniGene:
Mm.33903
CCDS:
CCDS26514.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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