| Type | Description |
|---|---|
| Definition | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 10:37:00 | Post-crossing CCAs switch off their response to axon guidance cues, among which the secreted Semaphorin-3C (Sema3C), that act as attractants for pre-crossing axons on their way to the midline. This change is concomitant with an upregulation of the surface protein Ephrin-B1, which acts in CCAs to inhibit Sema3C signaling via interaction with the Neuropilin-1 (Nrp1) receptor. | 29779877 |
| 2019-09-21 10:48:00 | Taken together, epithelium-expressed SEMA3C plays a role in corneal epithelial wound closure and sensory nerve regeneration. | 30679185 |
| 2019-02-09 12:58:00 | Sema3c is a candidate that mediates interaction between cardiac neural crest cells and the second heart field during development of the outflow tract. | 28754980 |
| 2015-09-26 14:51:00 | analyzed a complementary set of ligand-specific and tissue-specific mutants to show that neural crest-derived SEMA3C activates NRP1 in the cardiac outflow tract endothelium | 26053665 |
| 2013-08-03 10:50:00 | Sema3A overrides the effects of Sema3C in cortical axons exposed to defined mixtures of these opposing guidance cues in vitro | 22368082 |
| Type | IDs |
|---|---|
| Synonymous | 1110036B02Rik, SemE, Semae |
| Gene |
UniProtKB-ID:
SEM3C_MOUSE
UniprotKB:
Q62181
UniParc:
UPI0000022FC1
EMBL:
CH466586,
BC066852,
X85994
Ensembl:
ENSMUSG00000028780
KO:
mmu:20348
|
| Nucleutide sequences |
EMBL-CDS:
AAH66852.1,
CAA59986.1,
EDL03234.1
Ensembl_TRS:
ENSMUST00000030568
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030568
RefSeq:
NP_038685.3
|
| Others |
UniRef100:
UniRef100_Q62181
UniRef90:
UniRef90_Q62181
UniRef50:
UniRef50_Q62181
UniGene:
Mm.5071
CCDS:
CCDS19099.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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