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20347 Sema3b

20347

Sema3b

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

protein-coding

Mus musculus

基因描述

Type Description
Definition sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

研究结论

Date Results Publications
2020-06-27 10:07:00 CHL1 mediated spine pruning in response to Sema3B and associated with receptor subunits Neuropilin-2 and PlexinA4. Sema3B protein eliminated spines on apical dendrites of cortical neurons cultured from wild-type but not CHL1-null embryos. Sema3B was secreted by cortical neuron cultures.In vivo CHL1 was coexpressed with Sema3B in pyramidal neuron subpopulations and formed a complex with Neuropilin-2 and PlexinA4. 31182634
2016-11-12 10:18:00 Semaphorin3B may contribute to impaired bone formation by elevated TNF-alpha in estrogen-deficiency-induced osteoporosis. 26723579
2016-02-13 10:52:00 Cerebrospinal fluid-derived Semaphorin3B orients neuroepithelial cell divisions in the apicobasal axis. 25721514
2014-04-18 15:34:00 The human ortholog of this gene functions as a tumor suppressor gene. 11717452
2010-01-21 00:00:00 Dual functional activity of semaphorin 3B is required for positioning the anterior commissure. 16202709

名称对应

Type IDs
Synonymous SemA, Semaa, sema5, semaV
Gene
UniProtKB-ID: Q0VGP2_MOUSE, M9MMK0_MOUSE
UniprotKB: Q0VGP2, M9MMK0
UniParc: UPI00001C45A3, UPI0000DBE460
EMBL: AL672219, BC090669
Ensembl: ENSMUSG00000057969
KO: mmu:20347
Nucleutide sequences
EMBL-CDS: AAH90669.1
Ensembl_TRS: ENSMUST00000102532, ENSMUST00000102531, ENSMUST00000102530, ENSMUST00000073448, ENSMUST00000102529
Protein sequencees
Ensembl_PRO: ENSMUSP00000073152, ENSMUSP00000099590, ENSMUSP00000099588, ENSMUSP00000099589, ENSMUSP00000099591
RefSeq: XP_011241169.1, NP_001036244.1, XP_036010635.1, XP_006511727.1, NP_001278468.1, XP_011241165.1, XP_011241167.1, NP_001278467.1, XP_006511729.1, XP_011241166.1, NP_033179.2, XP_017168714.1, XP_011241164.1, XP_006511736.1, XP_006511728.1, XP_006511734.1, XP_036010636.1, NP_001278466.1
Others
UniRef100: UniRef100_Q0VGP2, UniRef100_M9MMK0
UniRef90: UniRef90_Q62177
UniRef50: UniRef50_Q13214-2
UniGene: Mm.4083

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