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20343 Sell

20343

Sell

selectin, lymphocyte

protein-coding

Mus musculus

基因描述

Type Description
Definition selectin, lymphocyte

研究结论

Date Results Publications
2020-02-22 11:54:00 L-selectin-deficient mice are prone to pulmonary infection compared with wild-type controls. Mechanistically, L-selectin cleavage from the neutrophil surface triggered by integrin engagement is involved in neutrophil recruitment into the lung and bacterial clearance. 31366620
2019-11-09 11:29:00 this study shows that CD62L is a functional and phenotypic marker for circulating innate lymphoid cell precursors 30504420
2019-08-03 13:14:00 These findings suggest that interactions between MAdCAM-1 and alpha4beta7 integrin and/or unsulfated sLeX and L-selectin may become a dominant mechanism for inflammatory cell recruitment in the absence of 6-sulfo sLeX and contribute to more severe colitis phenotypes seen in mice deficient in both GlcNAc6ST-1 and GlcNAc6ST-2. 29350564
2019-06-08 13:02:00 evidence that chronic inflammation may promote tumor growth via induction of CD62L expression by MDSCs that can facilitate their migration to tumor and lymph nodes and modulation of their suppressor activity. 30251217
2018-05-26 10:14:00 data suggest that Ly6C(+)CD62L(+) infected monocytes served as a Trojan horse across the cerebral endothelium to induce brain infection. Therefore, CD62L should be considered as not only a temporally elicited antigen but also a disease-relevant leukocyte marker during the development of neurologic melioidosis. 27646437

名称对应

Type IDs
Synonymous AI528707, CD62L, L-selectin, LECAM-1, Lnhr, Ly-22, Ly-m22, Lyam-1, Lyam1
Gene
UniProtKB-ID: LYAM1_MOUSE, B1B506_MOUSE, Q3TCF3_MOUSE, Q3UV83_MOUSE
UniprotKB: P18337, B1B506, Q3TCF3, Q3UV83
UniParc: UPI00005B2703, UPI00001EDDE0, UPI000002764B
EMBL: M36058, BC052681, AK137509, AH003204, AK170753, AC110499, M36005, M25324, X14772, AB353767
Ensembl: ENSMUSG00000026581
KO: mmu:20343
Nucleutide sequences
EMBL-CDS: CAA32880.1, AAA39723.1, AAA39722.1, AAH52681.1, AAA39431.1, AAA75651.1, BAG12830.1, BAE42004.1, BAE23389.1
Ensembl_TRS: ENSMUST00000027871, ENSMUST00000192047
Protein sequencees
Ensembl_PRO: ENSMUSP00000027871, ENSMUSP00000142237
RefSeq: NP_035476.1, XP_006496780.1, XP_006496781.1, XP_030108193.1, NP_001157531.1, XP_030108191.1
Others
UniRef100: UniRef100_Q3TCF3, UniRef100_B1B506, UniRef100_P18337
UniRef90: UniRef90_P18337
UniRef50: UniRef50_P14151
UniGene: Mm.1461
CCDS: CCDS35753.1

全选

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