| Type | Description |
|---|---|
| Definition | sel-1 suppressor of lin-12-like (C. elegans) |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:53:00 | Sel1L-Hrd1 ER-associated degradation maintains beta cell identity via TGF-beta signaling. | 32182217 |
| 2019-10-05 10:58:00 | This study not only establishes the importance of Sel1L-Hrd1 ERAD in the liver in the regulation of systemic energy metabolism, but also reveals a novel hepatic "ERAD-Crebh-Fgf21" axis directly linking ER protein turnover to gene transcription and systemic metabolic regulation. | 30389665 |
| 2018-12-22 11:18:00 | he drastic phenotypic characteristics exhibited in mSEL-1L null mice can, in part, be explained by the negative influence it plays on Notch1 signaling pathway. | 28816361 |
| 2017-11-25 15:32:00 | This study implicates Endoplasmic reticulum (ER)-associated degradation mediated by Sel1L-Hrd1 as a key regulator of B cell development. | 27568564 |
| 2017-10-28 13:15:00 | Mice deficient for ERAD machinery component Sel1L develop central diabetes insipidus | 28920918 |
| Type | IDs |
|---|---|
| Synonymous | AW493766, Sel1h, mKIAA4137 |
| Gene |
UniProtKB-ID:
SE1L1_MOUSE,
Q6GTY4_MOUSE,
Q5DTL8_MOUSE
UniprotKB:
Q9Z2G6,
Q6GTY4,
Q5DTL8
UniParc:
UPI0000001A2B,
UPI00004E1766,
UPI0000021A97
EMBL:
BC026816,
AF063095,
AK005023,
AK220502,
AK160936
Ensembl:
ENSMUSG00000020964
KO:
mmu:20338
|
| Nucleutide sequences |
EMBL-CDS:
AAD05210.1,
BAB23750.1,
AAH26816.1,
BAE36100.1,
BAD90512.1
Ensembl_TRS:
ENSMUST00000167466,
ENSMUST00000021347
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000021347,
ENSMUSP00000129384
RefSeq:
NP_001034178.1,
NP_035474.1
|
| Others |
UniRef100:
UniRef100_Q9Z2G6,
UniRef100_Q6GTY4
UniRef90:
UniRef90_Q9UBV2,
UniRef90_Q9Z2G6
UniRef50:
UniRef50_Q9UBV2
UniGene:
Mm.250605
CCDS:
CCDS26091.1,
CCDS49137.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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