| Type | Description |
|---|---|
| Definition | sodium channel, voltage-gated, type IX, alpha |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 10:48:00 | Nav1.7 and MGO-mediated activation of TRPA1 play key roles in itch and hypoalgesia in a murine model of type 1 diabetes. | 31285762 |
| 2020-04-11 10:19:00 | data illustrated the therapeutic potential for 3'-O-methylorobol for histamine-dependent itching, and the small molecule inhibition of Nav1.7 may represent a useful strategy to develop novel therapeutics for itching. | 31805638 |
| 2019-04-06 11:52:00 | This study demonstrated that nav1.7 contribution to peripheral nerves pain. | 29194125 |
| 2018-10-13 10:49:00 | Nav1.7, known to regulate opioid receptor efficacy, interacts with the G protein-regulated inducer of neurite outgrowth (Gprin1), an opioid receptor-binding protein, demonstrating a physical and functional link between Nav1.7 and opioid signalling. | 29335280 |
| 2018-04-07 11:10:00 | the NaV1.7 channel is an important mechanism underlying hyperalgesia | 28562485 |
| Type | IDs |
|---|---|
| Synonymous | Nav1.7, PN1, mKIAA4197 |
| Gene |
UniProtKB-ID:
SCN9A_MOUSE,
B1AYL0_MOUSE,
E9PW82_MOUSE
UniprotKB:
Q62205,
B1AYL0,
E9PW82
UniParc:
UPI0001D64380,
UPI000060418A,
UPI000060418B
EMBL:
AL928623,
AL928726,
AK220540,
L42338
Ensembl:
ENSMUSG00000075316
KO:
mmu:20274
|
| Nucleutide sequences |
EMBL-CDS:
AAA67106.1,
BAD90315.1
Ensembl_TRS:
ENSMUST00000100064,
ENSMUST00000164384,
ENSMUST00000112354,
ENSMUST00000169900
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000097642,
ENSMUSP00000126528,
ENSMUSP00000107973,
ENSMUSP00000131711
RefSeq:
NP_001277604.1,
NP_001277603.1,
XP_006499096.1,
XP_006499098.1
|
| Others |
UniRef100:
UniRef100_E9PW82,
UniRef100_Q62205,
UniRef100_B1AYL0
UniRef90:
UniRef90_Q62205
UniRef50:
UniRef50_Q62205
UniGene:
Mm.440889
CCDS:
CCDS71063.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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