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20273 Scn8a

20273

Scn8a

sodium channel, voltage-gated, type VIII, alpha

protein-coding

Mus musculus

基因描述

Type Description
Definition sodium channel, voltage-gated, type VIII, alpha

研究结论

Date Results Publications
2021-02-06 13:56:00 Mutations in the Scn8a DIIS4 voltage sensor reveal new distinctions among hypomorphic and null Nav 1.6 sodium channels. 31605437
2021-01-02 12:52:00 Sodium channel Nav1.6 in sensory neurons contributes to vincristine-induced allodynia. 32830219
2020-10-31 13:18:00 Amyloid beta-Induced Upregulation of Nav1.6 Underlies Neuronal Hyperactivity in Tg2576 Alzheimer's Disease Mouse Model. 31537873
2020-09-19 16:24:00 Normal audiogram but poor sensitivity to brief sounds in mice with compromised voltage-gated sodium channels (Scn8a(medJ)). 30669034
2020-08-15 19:05:00 NaV 1.6 regulates excitability of mechanosensitive sensory neurons. 31087362

名称对应

Type IDs
Synonymous AI853486, C630029C19Rik, NaCh6, Nav1.6, dmu, med, mnd-2, mnd2, nmf2, nmf335, nmf58, nur14, seal
Gene
UniProtKB-ID: SCN8A_MOUSE, F7D6K4_MOUSE, A0A0R5RP22_MOUSE, A0A0J9YUW5_MOUSE, F6U329_MOUSE, F7D6J5_MOUSE
UniprotKB: Q9WTU3, F7D6K4, A0A0R5RP22, A0A0J9YUW5, F6U329, F7D6J5
UniParc: UPI00001BB3D2, UPI0000028774, UPI0000028CBA, UPI00001BB3D3, UPI0003D7359B, UPI000645488A, UPI0000E67209, UPI0003D78DA6, UPI00001E9EDD, UPI00001BB3D1
EMBL: U59963, U23158, AF049617, U59964, KM373694, KM373693, U26707, AC104834, AK158609, AC104833
Ensembl: ENSMUSG00000023033
KO: mmu:20273
Nucleutide sequences
EMBL-CDS: AAC52708.1, AAC52242.1, AAD20438.1, AAA65599.1, BAE34580.1, AIW80046.1, AIW80045.1
Ensembl_TRS: ENSMUST00000108908, ENSMUST00000108910, ENSMUST00000200963, ENSMUST00000082209, ENSMUST00000201549, ENSMUST00000108909
Protein sequencees
Ensembl_PRO: ENSMUSP00000104536, ENSMUSP00000104538, ENSMUSP00000144371, ENSMUSP00000144013, ENSMUSP00000080842, ENSMUSP00000104537
RefSeq: XP_006520718.1, NP_001070967.1, XP_006520714.1, XP_017172002.1, XP_017172006.1, XP_006520719.1, XP_017172003.1, XP_017172008.1, XP_017172004.1, NP_035453.2, XP_017172001.1, XP_017172005.1
Others
UniRef100: UniRef100_Q9WTU3, UniRef100_A0A0R5RP22, UniRef100_F7D6J5, UniRef100_F7D6K4, UniRef100_A0A0J9YUW5, UniRef100_F6U329
UniRef90: UniRef90_Q9WTU3-3, UniRef90_Q9WTU3
UniRef50: UniRef50_Q9UQD0
UniGene: Mm.385012
CCDS: CCDS57011.1

全选

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