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20271 Scn5a

20271

Scn5a

sodium channel, voltage-gated, type V, alpha

protein-coding

Mus musculus

基因描述

Type Description
Definition sodium channel, voltage-gated, type V, alpha

研究结论

Date Results Publications
2021-03-28 19:07:00 Vascular endothelial growth factor promotes atrial arrhythmias by inducing acute intercalated disk remodeling. 33235263
2020-12-12 13:23:00 Protein expression profiles in murine ventricles modeling catecholaminergic polymorphic ventricular tachycardia: effects of genotype and sex. 32713021
2020-07-18 12:20:00 Luciferase reporter assays performed in HEK 293 cells and HL-1 revealed that LF3 increased the SCN5A promoter activity in HL-1 cells and prevented beta-catenin suppressive effect on SCN5A promoter activity in HEK 293 cells. 31419437
2020-04-04 12:48:00 Scn5a+/- heart ventricular slices showed longer refractory periods than wild-type hearts. 31291141
2020-02-29 10:48:00 Results show that mice carrying the homologous Scn5a-p.Y1981N mutation showed no electrical disturbances nor alterations in (late) induced sodium current and action potential properties. 31614475

名称对应

Type IDs
Synonymous Nav1.5, Nav1.5c, SkM1, SkM2, mH1
Gene
UniProtKB-ID: SCN5A_MOUSE, K3W4N7_MOUSE, Q8C3I3_MOUSE, A0A0R4J1M7_MOUSE
UniprotKB: Q9JJV9, K3W4N7, Q8C3I3, A0A0R4J1M7
UniParc: UPI00005AC617, UPI00023B1D93, UPI000173A71E, UPI000217CB63, UPI00000E9F08
EMBL: AK147517, AJ271477, AK085822, AK147254, AC121922, AC171201
Ensembl: ENSMUSG00000032511
KO: mmu:20271
Nucleutide sequences
EMBL-CDS: CAB70096.1, BAE27800.1, BAE27966.1, BAC39544.1
Ensembl_TRS: ENSMUST00000120420, ENSMUST00000065196, ENSMUST00000117911
Protein sequencees
Ensembl_PRO: ENSMUSP00000113272, ENSMUSP00000066228, ENSMUSP00000112838
RefSeq: NP_001240789.1, XP_006512058.1, XP_006512059.1, XP_006512060.1, NP_067519.2, XP_006512056.1
Others
UniRef100: UniRef100_Q8C3I3, UniRef100_Q9JJV9, UniRef100_A0A0R4J1M7, UniRef100_K3W4N7
UniRef90: UniRef90_Q8C3I3, UniRef90_Q9JJV9
UniRef50: UniRef50_Q14524, UniRef50_Q8C3I3
UniGene: Mm.103584

全选

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