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20266 Scn1b

20266

Scn1b

sodium channel, voltage-gated, type I, beta

protein-coding

Mus musculus

基因描述

Type Description
Definition sodium channel, voltage-gated, type I, beta

研究结论

Date Results Publications
2021-01-16 15:54:00 Sodium channel beta1 subunits are post-translationally modified by tyrosine phosphorylation, S-palmitoylation, and regulated intramembrane proteolysis. 32503841
2020-11-21 13:11:00 Delayed maturation of GABAergic signaling in the Scn1a and Scn1b mouse models of Dravet Syndrome. 30996233
2017-07-08 10:49:00 This study demonstrated that the sodium channel beta1 subunit proteins encoded by this mutant gene are expressed at the surface of neuronal cell bodies. 27277800
2015-12-19 11:57:00 Loss of Scn1b caused increased amplitude of tetrodotoxin-sensitive INa, delayed after-depolarizations, triggered beats, changed Ca2+ transients,and susceptibility ventricular arrhythmias. 25772295
2015-10-03 10:46:00 Study showed that Scn1b is widely expressed at axon initial segments across the mouse brain, there is considerable heterogeneity in the proportion of Scn1b-positive neurons and the amount of expression between and within brain regions 25421039

名称对应

Type IDs
Gene
UniProtKB-ID: SCN1B_MOUSE
UniprotKB: P97952
UniParc: UPI00000018D1
EMBL: U46681, BC039140, U85786, BC009652
Ensembl: ENSMUSG00000019194
KO: mmu:20266
Nucleutide sequences
EMBL-CDS: AAH09652.1, AAH39140.1, AAC53006.1, AAB49368.1
Ensembl_TRS: ENSMUST00000098548, ENSMUST00000211945
Protein sequencees
Ensembl_PRO: ENSMUSP00000148295, ENSMUSP00000096148
RefSeq: NP_035452.1, XP_030098118.1
Others
UniRef100: UniRef100_P97952
UniRef90: UniRef90_Q07699
UniRef50: UniRef50_Q07699
UniGene: Mm.1418
CCDS: CCDS21126.1

全选

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研究热度

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