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20257 Stmn2

20257

Stmn2

stathmin-like 2

protein-coding

Mus musculus

基因描述

Type Description
Definition stathmin-like 2

研究结论

Date Results Publications
2021-02-06 13:52:00 Stathmin-2 Mediates Glucagon Secretion From Pancreatic alpha-Cells. 32117057
2020-03-07 11:08:00 Stmn2 reduction in the mouse midbrain causes dopaminergic neuron degeneration, phosphorylated alpha-synuclein elevation, and locomotor deficits. STMN2 functions in synaptic trafficking in mouse dopaminergic neurons. 31748532
2018-02-10 11:11:00 autophagy induction stabilized microtubules by degrading SCG10, a microtubule disassembly protein in neurons. In mice with spinal cord injury, local administration of a specific autophagy-inducing peptide, Tat-beclin1, to lesion sites markedly attenuated axonal retraction of spinal dorsal column axons and cortical spinal tract and promoted regeneration of descending axons following long-term observation 27638205
2014-07-26 10:49:00 SCG10 promotes non-amyloidogenic processing of amyloid precursor protein by facilitating its trafficking to the cell surface. 23863461
2014-03-15 10:48:00 This study demonstrated that axonal injury induces a dynamic regulation of SCG10 protein levels with selective accumulation in proximal axon segments. 24246279

名称对应

Type IDs
Synonymous AI159727, SCG10, Scgn10, Stmb2
Gene
UniProtKB-ID: STMN2_MOUSE, Q545S4_MOUSE
UniprotKB: P55821, Q545S4
UniParc: UPI0000000C77
EMBL: L20261, L20259, L20262, L20263, BC026538, AK003659, L20260, AK149212
Ensembl: ENSMUSG00000027500
KO: mmu:20257
Nucleutide sequences
EMBL-CDS: AAH26538.1, BAE28766.1, BAB22921.1
Ensembl_TRS: ENSMUST00000029002
Protein sequencees
Ensembl_PRO: ENSMUSP00000029002
RefSeq: NP_079561.1
Others
UniRef100: UniRef100_Q93045
UniRef90: UniRef90_Q93045
UniRef50: UniRef50_Q93045
UniGene: Mm.29580
CCDS: CCDS17231.1

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

Howard Hughes Medical Institute

5
2

California Institute of Technology

3
3

Institut de Génétique et de Biologie Moléculaire et Cellulaire

3
4

CNRS/INSERM/Université Louis Pasteur

3
5

Tongji University School of Medicine

3
热点人员
排名 研究人员 文献
1

F Guillemot

9
2

D J Anderson

8
3

P Carninci

7
4

Y Hayashizaki

6
5

Carol Schuurmans

6
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