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20255 Scg3

20255

Scg3

secretogranin III

protein-coding

Mus musculus

基因描述

Type Description
Definition secretogranin III

研究结论

Date Results Publications
2018-10-27 12:00:00 This review summarizes our current knowledge of Scg3 as a regulatory protein of secretory granules, highlights its new role as a highly disease-selective angiogenic factor, and envisions Scg3 inhibitors as "selective angiogenesis blockers" for targeted therapy of diabetic retinopathy.[ review] 28856381
2016-10-08 11:41:00 we show by RNA silencing that CPE and SgIII play a synergistic role in the trafficking of POMC to granules of the regulated secretory pathway in AtT20 cells 26646096
2013-06-15 11:04:00 SgIII knockdown impairs intracellular retention of chromogranin A and proopiomelanocortin in AtT-20 cells. 23171199
2010-10-30 11:14:00 The robust expression of SgIII in astrocytes and its regulation in the injured brain suggest both intracellular and extracellular roles for this glial granin in the physiology and repair/damage of neuronal circuits. 19892786
2010-01-21 00:00:00 SgIII directly binds to cholesterol components of the secretory granule membrane and targets chromogranin A to secretory granules in pituitary and pancreatic endocrine cells 14597614

名称对应

Type IDs
Synonymous 1B1075, AI385542, Chgd, SgIII
Gene
UniProtKB-ID: SCG3_MOUSE
UniprotKB: P47867
UniParc: UPI00000E840A, UPI00000239D0
EMBL: AK139140, BC024785, AK158315, U02982, CH466522, AK164089, AK133655
Ensembl: ENSMUSG00000032181
KO: mmu:20255
Nucleutide sequences
EMBL-CDS: BAE23899.1, BAE34456.1, BAE37620.1, AAH24785.1, BAE21767.1, AAA56636.1, EDL26334.1
Ensembl_TRS: ENSMUST00000213324, ENSMUST00000034699
Protein sequencees
Ensembl_PRO: ENSMUSP00000034699, ENSMUSP00000149561
RefSeq: NP_033156.1, XP_006510944.1, NP_001158262.1, XP_017168709.1
Others
UniRef100: UniRef100_P47867
UniRef90: UniRef90_P47867
UniRef50: UniRef50_Q8WXD2
UniGene: Mm.2386
CCDS: CCDS23347.1, CCDS90627.1

全选

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