| Type | Description |
|---|---|
| Definition | ataxin 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:12:00 | TGF-beta regulates Sca-1 expression and plasticity of pre-neoplastic mammary epithelial stem cells. | 32647280 |
| 2020-11-21 13:22:00 | Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis. | 32878998 |
| 2020-09-05 13:59:00 | The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways. | 32620905 |
| 2020-05-16 12:49:00 | Knockout of Atxn1 reduced CIC-ETV4/5-mediated inhibition of Bace1 transcription, leading to increased BACE1 levels and enhanced amyloidogenic cleavage of APP, selectively in AD-vulnerable brain regions. | 31442405 |
| 2019-09-14 12:31:00 | expanded ATXN1 stimulates the proliferation of postnatal cerebellar stem cells in SCA1 mice. These hyperproliferating stem cells tended to differentiate into GABAergic inhibitory interneurons rather than astrocytes; this significantly increased the GABAergic inhibitory interneuron synaptic connections, disrupting cerebellar Purkinje cell function in a non-cell autonomous manner. | 29533923 |
| Type | IDs |
|---|---|
| Synonymous | 2900016G23Rik, Atx1, C85907, Gm10786, Sca1 |
| Gene |
UniProtKB-ID:
ATX1_MOUSE,
J3QPR1_MOUSE
UniprotKB:
P54254,
J3QPR1
UniParc:
UPI0000F4A96C,
UPI00000245B3
EMBL:
AC154401,
AK048268,
BC058178,
AC154817,
AC126426,
X83542,
AC154733
Ensembl:
ENSMUSG00000046876
KO:
mmu:20238
|
| Nucleutide sequences |
EMBL-CDS:
CAA58533.1,
AAH58178.1,
BAC33290.1
Ensembl_TRS:
ENSMUST00000167708,
ENSMUST00000091628,
ENSMUST00000180110
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129890,
ENSMUSP00000089217,
ENSMUSP00000137439
RefSeq:
XP_011242694.1,
NP_033150.2,
XP_030103073.1,
XP_011242692.1,
XP_030103071.1,
XP_011242688.1,
XP_030103070.1,
XP_011242683.1,
XP_017170952.1,
XP_011242687.1,
XP_011242693.1,
NP_001186234.1,
XP_036013836.1,
XP_011242685.1,
XP_011242691.1,
XP_011242690.1,
NP_001186233.1,
XP_036013837.1,
XP_030103072.1,
XP_011242689.1
|
| Others |
UniRef100:
UniRef100_J3QPR1,
UniRef100_P54254
UniRef90:
UniRef90_P54254,
UniRef90_J3QPR1
UniRef50:
UniRef50_P54253
UniGene:
Mm.342683,
Mm.342686,
Mm.486641,
Mm.487047
CCDS:
CCDS26483.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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