| Type | Description |
|---|---|
| Definition | serum amyloid P-component |
| Date | Results | Publications |
|---|---|---|
| 2016-10-22 11:31:00 | SAP deficiency mitigated foam cell formation and atherosclerotic development in apoE(-/-) mice, due to reduction in macrophages recruitment, polarization and pro-inflammatory cytokines | 26649902 |
| 2015-10-31 11:04:00 | Data suggest that serum amyloid P (SAP) activates CD209 DC-SIGN to regulate the innate immune system differently from C-reactive protein (CRP), and that DC-SIGN is a target for antifibrotics. | 26106150 |
| 2012-12-22 11:36:00 | observations suggest that serum amyloid P, at least in part, uses FcgammaRI and FcRgamma to inhibit fibrocyte differentiation | 22493081 |
| 2012-07-21 11:25:00 | Bglu3 is confirmed to be a locus affecting diabetes susceptibility, and Apcs is a probable candidate gene. | 22274563 |
| 2011-10-01 12:07:00 | binding of SAP to ALD-DNA could switch macrophage phenotypic polarization from proinflammatory M2b to anti-inflammatory M2a via PI3K/Akt-ERK signaling activation, thus exerting protective and therapeutic interventions on murine lupus nephritis | 21753147 |
| Type | IDs |
|---|---|
| Synonymous | Sap |
| Gene |
UniProtKB-ID:
SAMP_MOUSE,
Q4JFI8_MOUSE
UniprotKB:
P12246,
Q4JFI8
UniParc:
UPI0000022928
EMBL:
Y00426,
AK165699,
X14079,
HQ283363,
X16899,
AK144248,
M23552,
M29535,
S40320,
M23248,
BC061125
Ensembl:
ENSMUSG00000026542
KO:
mmu:20219
|
| Nucleutide sequences |
EMBL-CDS:
CAA68488.1,
AAA40093.1,
CAA32243.1,
CAA34774.1,
AAH61125.1,
AAA40091.1,
AAA40092.1,
AAY88178.1,
BAE38344.1,
BAE25796.1,
ADZ99751.1
Ensembl_TRS:
ENSMUST00000027824
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000027824
RefSeq:
NP_035448.2
|
| Others |
UniRef100:
UniRef100_P12246
UniRef90:
UniRef90_P12246
UniRef50:
UniRef50_P12246
UniGene:
Mm.330510
CCDS:
CCDS15520.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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