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2021 ENDOG

2021

ENDOG

endonuclease G

protein-coding

Homo sapiens

基因描述

Type Description
Definition endonuclease G

研究结论

Date Results Publications
2019-03-02 10:50:00 EndoG is an endonuclease with the unique ability to inactivate another endonuclease, DNase I, and to modulate the development of apoptosis. 30521874
2018-06-09 10:04:00 These data indicated the participation of EndoG in alternative mRNA splicing of the telomerase catalytic subunit hTERT, regulation of telomerase activity and determination of cell fate. 28886883
2017-06-24 11:41:00 Galectin-3-induced cell death in HIV-1-infected macrophages is most likely related to the translocation of Endo G from the cytoplasm to the nucleus. 27981746
2017-03-25 11:49:00 ndoG digests long non-coding RNA and produces 47-mer RNA oligonucleotide complementary to hTERT pre-mRNA exon 8 and intron 8 junction place. Interaction of 47-mer RNA oligonucleotide and hTERT pre-mRNA causes alternative splicing. 27797329
2017-03-25 11:42:00 Overexpression of EndoG in CD4+ T cells downregulated the expression of the active full-length hTERT variant and upregulated the inactive alternatively spliced variant. 28320284

名称对应

Type IDs
Gene
UniProtKB-ID: NUCG_HUMAN, E5KNL5_HUMAN
UniprotKB: Q14249, E5KNL5
UniParc: UPI000013E66E
EMBL: HQ205325, HQ205309, HQ205329, HQ205327, HQ205344, HQ205345, HQ205339, HQ205313, HQ205343, HQ205341, HQ205314, HQ205337, HQ205319, HQ205326, HQ205312, HQ205335, HQ205328, HQ205311, HQ205338, BC004922, HQ205324, HQ205316, HQ205340, HQ205307, HQ205306, HQ205336, AL441992, HQ205317, HQ205334, HQ205332, HQ205330, HQ205331, HQ205310, HQ205321, HQ205315, HQ205318, HQ205333, HQ205320, X79444, HQ205308, HQ205322, HQ205342, HQ205323, BC016351
Ensembl: ENSG00000167136
KO: hsa:2021
Nucleutide sequences
EMBL-CDS: AAH04922.1, AAH16351.1, CAA55963.1, ADP90783.1, ADP90784.1, ADP90788.1, ADP90780.1, ADP90777.1, ADP90800.1, ADP90806.1, ADP90787.1, ADP90799.1, ADP90785.1, ADP90789.1, ADP90811.1, ADP90792.1, ADP90776.1, ADP90786.1, ADP90782.1, ADP90794.1, ADP90790.1, ADP90791.1, ADP90796.1, ADP90774.1, ADP90775.1, ADP90813.1, ADP90798.1, ADP90807.1, ADP90781.1, ADP90779.1, ADP90805.1, ADP90809.1, ADP90808.1, ADP90804.1, ADP90803.1, ADP90802.1, ADP90778.1, ADP90801.1, ADP90793.1, ADP90812.1, ADP90797.1, ADP90810.1, ADP90795.1
Ensembl_TRS: ENST00000372642
Protein sequencees
Ensembl_PRO: ENSP00000361725
RefSeq: XP_011516649.1, NP_004426.2
Others
UniRef100: UniRef100_Q14249
UniRef90: UniRef90_Q14249
UniRef50: UniRef50_O08600
UniGene: Hs.745161
CCDS: CCDS6912.1

全选

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研究热度

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