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20208 Saa1

20208

Saa1

serum amyloid A 1

protein-coding

Mus musculus

基因描述

Type Description
Definition serum amyloid A 1

研究结论

Date Results Publications
2020-10-24 14:10:00 Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity. 32572240
2020-10-24 13:59:00 Serum amyloid A exhibits pH dependent antibacterial action and contributes to host defense against Staphylococcus aureus cutaneous infection. 31819008
2020-07-04 12:06:00 Comparisons between APP and APP/SAA1 transgenic mice showed that SAA1 exacerbated amyloid aggregation and glial activation; which lead to the memory decline. Behavior tests also supported this result. Overall, overexpression of SAA1 intensified the neuronal inflammation in amyloid abundant condition and causes the greater memory decline compared to APP mice, which only expresses Abeta 1-42 31407125
2020-02-29 11:33:00 SAA and sPLA2 can act synergistically to remove cellular membrane debris from injured sites, which is a prerequisite for tissue healing. 31111824
2019-06-01 11:32:00 This study confirmed that SAA1 was a prominent protein that increased IL-17 levels through TLR2 in gammadelta T cells, confirming the possibility that SAA1 may exacerbate inflammatory diseases through gammadelta T cells. 30892738

名称对应

Type IDs
Synonymous Saa-1, Saa2
Gene
UniProtKB-ID: SAA1_MOUSE, Q5I0U6_MOUSE
UniprotKB: P05366, Q5I0U6
UniParc: UPI0000020FCD
EMBL: M13521, BC087933, M11131
Ensembl: ENSMUSG00000074115
KO: mmu:20208
Nucleutide sequences
EMBL-CDS: AAA40084.1, AAA40083.1, AAH87933.1
Ensembl_TRS: ENSMUST00000128088
Protein sequencees
Ensembl_PRO: ENSMUSP00000119150
RefSeq: XP_006540788.1, NP_033143.1, XP_006540787.1, NP_001344422.1
Others
UniRef100: UniRef100_P05366
UniRef90: UniRef90_P05366
UniRef50: UniRef50_P05366
UniGene: Mm.148800
CCDS: CCDS21284.1

全选

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研究热度

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