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201973 PRIMPOL

201973

PRIMPOL

primase and DNA directed polymerase

protein-coding

Homo sapiens

基因描述

Type Description
Definition primase and DNA directed polymerase

研究结论

Date Results Publications
2021-03-06 13:30:00 Strand Displacement Activity of PrimPol. 33261049
2021-01-16 16:00:00 The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization. 33237263
2020-12-19 13:45:00 PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts. 33203852
2020-08-22 15:30:00 A cancer-associated point mutation disables the steric gate of human PrimPol. 30718533
2020-01-11 11:25:00 PrimPol active site requires a specific motif A (DxE) to favor the use of Mn(2+) ions in order to achieve optimal incoming nucleotide stabilization 30889508

名称对应

Type IDs
Synonymous CCDC111, MYP22, Primpol1
Gene
UniProtKB-ID: PRIPO_HUMAN, A0A5S6SZ32_HUMAN
UniprotKB: Q96LW4, A0A5S6SZ32
UniParc: UPI000006F616, UPI0000EE2D45, UPI0000EE2D46
EMBL: AK057729, BC064600, AC079257, BX647575, CH471056, KF459591
Ensembl: ENSG00000164306
KO: hsa:201973
Nucleutide sequences
EMBL-CDS: AAH64600.1, EAX04669.1, EAX04670.1, EAX04667.1, CAI46079.1, BAB71553.1, EAX04668.1, EAX04671.1
Gene_ORFName: hCG_1786938
Ensembl_TRS: ENST00000314970, ENST00000512834, ENST00000503752, ENST00000515774
Protein sequencees
Ensembl_PRO: ENSP00000425316, ENSP00000313816, ENSP00000420860, ENSP00000421913
RefSeq: XP_016863357.1, XP_016863358.1, NP_001332830.1, NP_001287696.1, XP_011530026.1, NP_001332828.1, XP_011530032.1, NP_001332821.1, NP_001332822.1, XP_024309699.1, NP_001332826.1, NP_001332820.1, XP_011530027.1, NP_001332824.1, XP_011530028.1, NP_001332823.1, NP_001332829.1, XP_016863356.1, XP_016863361.1, XP_024309697.1, NP_001332827.1, NP_689896.1, XP_024309700.1, NP_001332825.1, NP_001287697.1, XP_024309701.1, XP_024309696.1, XP_011530022.1, XP_024309702.1, XP_011530025.1, XP_024309698.1
Others
UniRef100: UniRef100_Q96LW4
UniRef90: UniRef90_Q96LW4
UniRef50: UniRef50_Q96LW4
UniGene: Hs.481307
CCDS: CCDS75211.1, CCDS3837.1

全选

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