| Type | Description |
|---|---|
| Definition | engrailed homeobox 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:51:00 | Engrailed Homeobox 1 and Cytokeratin 19 Are Independent Diagnostic Markers of Eccrine Porocarcinoma and Distinguish It From Squamous Cell Carcinoma. | 32556098 |
| 2020-06-20 10:06:00 | EN1 transcription factor regulates neurogenesis-related genes and is associated with brain metastasis in triple-negative breast cancer. | 31239270 |
| 2019-04-06 10:13:00 | Study found that EN1 was significantly overexpressed in triple-negative breast cancer (TNBC). In breast cancer cell lines EN1 was more highly expressed in TNBC than in other breast cancer subtypes. EN1 expressions analysis in TNBC tissue samples revealed that EN1 protein expression was positively associated with reduced overall survival rate in patients with quintuple-negative, but not those with basal-like breast cancer. | 29333926 |
| 2018-09-29 11:54:00 | Engrailed homeobox 1 was expressed specifically in normal eccrine glands and was expressed in most of the tumour cells of sweat gland neoplasms with eccrine gland differentiation. | 29436004 |
| 2018-03-31 11:39:00 | our finding suggested that the EN1 rs4144782 might contribute to the susceptibility of knee OA. | 28430581 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HME1_HUMAN
UniprotKB:
Q05925
UniParc:
UPI000013E21D
EMBL:
L12698,
CH471103,
AC012665,
L12699
Ensembl:
ENSG00000163064
KO:
hsa:2019
|
| Nucleutide sequences |
EMBL-CDS:
AAX88967.1,
AAA53502.2,
EAW95206.1
Ensembl_TRS:
ENST00000295206
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000295206
RefSeq:
NP_001417.3
|
| Others |
UniRef100:
UniRef100_Q05925
UniRef90:
UniRef90_Q05925
UniRef50:
UniRef50_Q05925
UniGene:
Hs.271977
CCDS:
CCDS2123.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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