| Type | Description |
|---|---|
| Definition | HPS6, biogenesis of lysosomal organelles complex 2 subunit 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:15:00 | VWF maturation and release are controlled by 2 regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2. | 32614949 |
| 2020-02-01 11:51:00 | This study analyzed the plasma lipid profiles of three HPS mutant mice, pa (Hps9 (-/-)), ru (Hps6 (-/-)), ep (Hps1 (-/-)), and wild-type (WT) mice. The findings may provide clues to explain why different HPS mutant mice exhibit distinct anti-atherosclerotic or atherogenic effects after being exposed to high-cholesterol diets. | 30710063 |
| 2017-10-21 12:16:00 | BLOC-2 subunit HPS6 deficiency affects the tubulation and secretion of von Willebrand factor from mouse endothelial cells | 27889498 |
| 2015-08-01 10:58:00 | BLOC-2 functions to direct recycling endosomal tubular transport intermediates to maturing melanosomes and thereby promote cargo delivery and optimal pigmentation. | 26008744 |
| 2013-03-16 11:10:00 | The product of the Mreg(dsu) locus, melanoregulin (MREG), interacts both with members of BLOC-2 complex and with ocular albinism in regulating melanosome size. | 22984402 |
| Type | IDs |
|---|---|
| Synonymous | 5330434M19Rik, BLOC2, ru |
| Gene |
UniProtKB-ID:
HPS6_MOUSE
UniprotKB:
Q8BLY7
UniParc:
UPI0000003B35
EMBL:
AK030582,
AK159588,
AK040849,
AF536239,
BC034055
Ensembl:
ENSMUSG00000074811
KO:
mmu:20170
|
| Nucleutide sequences |
EMBL-CDS:
AAH34055.1,
BAC27030.1,
AAO25966.1,
BAC30719.1,
BAE35208.1
Ensembl_TRS:
ENSMUST00000099393
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000096991
RefSeq:
NP_789742.2
|
| Others |
UniRef100:
UniRef100_Q8BLY7
UniRef90:
UniRef90_Q8BLY7
UniRef50:
UniRef50_Q86YV9
UniGene:
Mm.101110
CCDS:
CCDS29869.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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