| Type | Description |
|---|---|
| Definition | dehydrogenase/reductase (SDR family) member 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-06-02 12:07:00 | Epicardial upregulation of DHRS3 gene Results in Defective Coronary Vessel Development. | 29689192 |
| 2018-05-04 17:10:00 | Yap targets Dhrs3, to reduce retinoic acid synthesis and inhibit cardiac fibroblast differentiation during development. | 29689192 |
| 2018-03-05 11:46:00 | Dhrs3 plays critical roles in the development of the heart and the coronary vasculature by controlling the formation of retinoic acid. | 29447006 |
| 2018-03-05 11:45:00 | DHRS3 is important in limiting the formation of retinoic acid to ensure the proper development of the coronary vasculature. | 29447006 |
| 2014-03-20 14:59:00 | DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development. Lack of DHRS3 leads to increases in the levels of retinoic acid, decreases in the levels of retinol and retinyl esters and changes in the expression of genes regulated by retinoic acid. As a result, Dhrs3-deficient embryos exhibit defects in the development of the heart, palate and skeleton and are not viable. | 24005908 |
| Type | IDs |
|---|---|
| Synonymous | Rsdr1, retSDR1 |
| Gene |
UniProtKB-ID:
DHRS3_MOUSE,
G5E8W9_MOUSE
UniprotKB:
O88876,
G5E8W9
UniParc:
UPI0000022F30,
UPI00000240C5,
UPI00001F1AF2
EMBL:
AL626773,
AL606909,
AF179240,
AF179238,
X95281,
AF179239,
BC008980,
AK032958,
AF179241,
AK151419,
BC013540,
AF061743,
BC010972
Ensembl:
ENSMUSG00000066026
KO:
mmu:20148
|
| Nucleutide sequences |
EMBL-CDS:
CAA64602.1,
AAD55403.1,
AAH08980.1,
BAC28098.1,
AAH13540.1,
BAE30384.1,
AAH10972.1,
AAC63265.1
Ensembl_TRS:
ENSMUST00000105744,
ENSMUST00000154208,
ENSMUST00000171001
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000122552,
ENSMUSP00000101370,
ENSMUSP00000126154
RefSeq:
NP_001165895.1,
NP_001344204.1,
XP_030109228.1,
NP_001344206.1,
NP_001344203.1,
XP_036019818.1,
NP_035433.1,
NP_001344205.1,
XP_006538744.1
|
| Others |
UniRef100:
UniRef100_O88876
UniRef90:
UniRef90_O88876
UniRef50:
UniRef50_O88876
UniGene:
Mm.14063
CCDS:
CCDS18912.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员