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201475 RAB12

201475

RAB12

RAB12, member RAS oncogene family

protein-coding

Homo sapiens

基因描述

Type Description
Definition RAB12, member RAS oncogene family

研究结论

Date Results Publications
2019-01-19 10:49:00 show that DENND3 binds actin through a surface of positively charged residues on the PHenn domain of Ran12 29352104
2017-07-15 10:17:00 DENND3 is the exchange factor for the small GTPase Rab12 regulated through an intramolecular interaction 28249939
2016-03-12 10:05:00 a novel signaling pathway identified whereby starvation-induced activation of ULK leads to phosphorylation of endogenous DENND3, with subsequent activation of Rab12 and initiation of membrane trafficking events required for autophagy 25925668
2015-02-28 13:05:00 findings demonstrate the functional importance of Rab12 for retrograde toxin trafficking 24703428

名称对应

Type IDs
Gene
UniProtKB-ID: RAB12_HUMAN
UniprotKB: Q6IQ22
UniParc: UPI00002019BA
EMBL: CH471113, AP001793, BC098407, BC071600, BC050338
Ensembl: ENSG00000206418
KO: hsa:201475
Nucleutide sequences
EMBL-CDS: AAH71600.2, AAH98407.1, EAX01616.1
Ensembl_TRS: ENST00000329286
Protein sequencees
Ensembl_PRO: ENSP00000331748
RefSeq: XP_006722363.1, NP_001020471.3
Others
UniRef100: UniRef100_Q6IQ22
UniRef90: UniRef90_Q6IQ22
UniRef50: UniRef50_Q6IQ22
UniGene: Hs.270074
CCDS: CCDS42410.1

全选

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研究热度

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