| Type | Description |
|---|---|
| Definition | aprataxin and PNKP like factor |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 10:43:00 | MIR888-dependent inhibition of APLF by E2F1 was demonstrated using overexpression and knockdown experiments, in combination with luciferase assays. | 31287003 |
| 2019-08-24 12:44:00 | The crystal structures of the Ku-binding motifs (KBM) of the non-homologous end joining (NHEJ) proteins APLF (A-KBM) and XLF (X-KBM) bound to a Ku-DNA complex are discussed. | 30291363 |
| 2019-08-03 12:10:00 | The acidic domain of APLF is a histone chaperone that can bind both the histone H2A-H2B dimer and H3-H4 tetramer. | 29905837 |
| 2019-08-03 10:20:00 | Data provided novel evidence for enrichment of APLF in breast tumors, which could regulate metastasis-associated epithelial-to-mesenchymal transition in invasive breast cancer. | 29580241 |
| 2017-12-30 10:57:00 | characterization of the interaction of the APLF FHA domain with phosphorylated XRCC1 peptides | 29059378 |
| Type | IDs |
|---|---|
| Synonymous | APFL, C2orf13, PALF, Xip1, ZCCHH1 |
| Gene |
UniProtKB-ID:
APLF_HUMAN
UniprotKB:
Q8IW19
UniParc:
UPI0000074578
EMBL:
AC127383,
AK290841,
AC130709,
BC041144,
AC105054
Ensembl:
ENSG00000169621
KO:
hsa:200558
|
| Nucleutide sequences |
EMBL-CDS:
AAY14945.1,
BAF83530.1,
AAY24008.1,
AAY24113.1,
AAH41144.1
Ensembl_TRS:
ENST00000303795
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000307004
RefSeq:
NP_775816.1
|
| Others |
UniRef100:
UniRef100_Q8IW19
UniRef90:
UniRef90_Q8IW19
UniRef50:
UniRef50_Q8IW19
UniGene:
Hs.720369
CCDS:
CCDS1888.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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