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200504 GKN2

200504

GKN2

gastrokine 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition gastrokine 2

研究结论

Date Results Publications
2020-10-24 14:10:00 Coordinate expression loss of GKN1 and GKN2 in gastric cancer via impairment of a glucocorticoid-responsive enhancer. 32538140
2020-02-15 13:17:00 Study computationally predicted and experimentally validated specific mechanisms of anticancer effects of GKN2 in gastric cancer proliferation and invasion in vitro. 31463974
2020-01-11 12:14:00 we demonstrated GKN2 might increase sensitivity of GC cells to the drugs which increase levels in tumors. Inhibition of the interaction between GKN2 and Hsc70 could attenuate the effects induced by GKN2. 31382983
2018-07-14 10:26:00 Co-expression of GKN2 and TFF1 massively suppressed the expression of positive cell cycle regulators and induced G1/S arrest, synergistically enhancing the inhibition of cell viability and proliferation of gastric cancer cells 28150071
2017-07-15 10:19:00 These findings suggested that GDDR expression was significantly associated with the progression of gastric cancer and GDDR may function as a tumor suppressor via inhibiting the epithelial-mesenchymal transition. 27017226

名称对应

Type IDs
Synonymous BRICD1B, GDDR, PRO813, TFIZ1, VLTI465
Gene
UniProtKB-ID: GKN2_HUMAN
UniprotKB: Q86XP6
UniParc: UPI0000160A98
EMBL: AJ966788, AY943908, AF494509, AY358664
Ensembl: ENSG00000183607
KO: hsa:200504
Nucleutide sequences
EMBL-CDS: AAY24521.1, AAQ89027.1, CAI85014.1, AAO85515.2
Gene_ORFName: UNQ465/PRO813
Ensembl_TRS: ENST00000328895
Protein sequencees
Ensembl_PRO: ENSP00000329292
RefSeq: NP_872342.2
Others
UniRef100: UniRef100_Q86XP6
UniRef90: UniRef90_Q86XP6
UniRef50: UniRef50_Q86XP6
UniGene: Hs.16757
CCDS: CCDS33215.1

全选

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研究热度

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