| Type | Description |
|---|---|
| Definition | apolipoprotein B mRNA editing enzyme catalytic subunit 3F |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 11:36:00 | analysis of the dependence of the deamination rate of human APOBEC3F on the length of single-stranded DNA, which is affected by the concentrations of APOBEC3F and single-stranded DNA | 30986508 |
| 2020-02-15 10:28:00 | The cryo-EM structure of the Vif-targeted C-terminal domain of human A3F in complex with HIV-1 Vif and the cellular cofactor core-binding factor beta (CBFbeta) at 3.9-A resolution shows that Vif and CBFbeta form a platform to recruit A3F, revealing a direct A3F-recruiting role of CBFbeta beyond Vif stabilization, and it captures multiple independent A3F-Vif interfaces. | 31792451 |
| 2019-03-09 10:53:00 | Apolipoprotein B mRNA editing enzyme catalytic subunit 3F (A3F) polymorphism A3F 231V restrict HIV-1 infection more efficiently than A3F 231 and is partially protected from Vif-mediated degradation. A3F 231V induces more mutations than A3F 231I in HIV-1 proviral DNA. A3F genotypes are commonly heterozygous. Hetero-oligomerization with A3F 231V results in partial stabilization of A3F 231I and A3G in the presence of Vif. | 30448640 |
| 2017-06-24 13:00:00 | APOBEC3DE binds to itself, APOBEC3F, and APOBEC3G and antagonizes APOBEC3F and, to a lesser extent, APOBEC3G restriction of hepatitis B virus replication. | 27289067 |
| 2017-06-24 11:24:00 | These results indicate that APOBEC3 proteins can be copackaged and can comutate the same genomes, and can cooperate to inhibit HIV replication. | 27439715 |
| Type | IDs |
|---|---|
| Synonymous | A3F, ARP8, BK150C2.4.MRNA, KA6 |
| Gene |
UniProtKB-ID:
ABC3F_HUMAN
UniprotKB:
Q8IUX4
UniParc:
UPI000016074C,
UPI000006E433,
UPI000034E5BC
EMBL:
BC038808,
BC061914,
DQ146365,
AL022318,
CR456395,
CH471095
Ensembl:
ENSG00000128394
KO:
hsa:200316
|
| Nucleutide sequences |
EMBL-CDS:
EAW60289.1,
AAZ38720.1,
AAH61914.1,
CAG30281.1,
EAW60288.1,
AAH38808.1
Ensembl_TRS:
ENST00000381565,
ENST00000308521
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000309749,
ENSP00000370977
RefSeq:
XP_024307947.1,
XP_016884132.1,
XP_024307946.1,
XP_016884131.1,
NP_660341.2,
NP_001006667.1
|
| Others |
UniRef100:
UniRef100_Q8IUX4
UniRef90:
UniRef90_Q8IUX4
UniRef50:
UniRef50_Q8IUX4
UniGene:
Hs.659809
CCDS:
CCDS33649.1,
CCDS33648.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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