| Type | Description |
|---|---|
| Definition | cytochrome P450 family 4 subfamily Z member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:57:00 | Importance of asparagine-381 and arginine-487 for substrate recognition in CYP4Z1. | 32044355 |
| 2020-05-16 10:56:00 | Transcriptional factor six2 promotes the competitive endogenous RNA network between CYP4Z1 and pseudogene CYP4Z2P responsible for maintaining the stemness of breast cancer cells. | 30832689 |
| 2019-12-28 10:52:00 | We recently demonstrated the presence of the human CYP4Z1 on the plasma membrane of MCF-7 breast cancer cells and the detection of high titers of anti-CYP4Z1 aAbs in breast cancer patients, but not in healthy controls. In the present study we show that cells of the normal breast cell line MCF-10A do not display CYP4Z1 on their surface. | 31082724 |
| 2018-07-21 11:52:00 | If CYP4Z1 has a role to play in modulating cancer progression, new data form yeast microsomes expressing recombinant human enzyme suggest that the mechanism does not involve direct 20-HETE generation by this enzyme. | 29018033 |
| 2017-12-16 12:11:00 | This study reports on the creation of a new homology model of CYP4Z1 and performed molecular docking experiments, which indicate that all active substrates show a highly similar binding geometry compared to the endogenous substrates. | 28951277 |
| Type | IDs |
|---|---|
| Synonymous | CYP4A20 |
| Gene |
UniProtKB-ID:
CP4Z1_HUMAN
UniprotKB:
Q86W10
UniParc:
UPI00000477F8
EMBL:
AL135960,
AL450996,
AK292175,
AY358631,
AY262056
Ensembl:
ENSG00000186160
KO:
hsa:199974
|
| Nucleutide sequences |
EMBL-CDS:
AAQ88994.1,
CAH71036.1,
AAO89257.1,
BAF84864.1,
CAI19734.1
Gene_ORFName:
UNQ3060/PRO9882
Ensembl_TRS:
ENST00000334194
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000334246
RefSeq:
XP_024309624.1,
NP_835235.1
|
| Others |
UniRef100:
UniRef100_Q86W10
UniRef90:
UniRef90_Q86W10
UniRef50:
UniRef50_Q86W10
UniGene:
Hs.176588
CCDS:
CCDS545.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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