| Type | Description |
|---|---|
| Definition | NLR family pyrin domain containing 7 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:16:00 | NLRP7 plays a functional role in regulating BMP4 signaling during differentiation of patient-derived trophoblasts. | 32814763 |
| 2021-01-23 12:59:00 | Abnormal processing of IL-1beta in NLRP7-mutated monocytes in hydatidiform mole patients. | 32484253 |
| 2020-08-01 11:43:00 | the atypical features of hydatidiform moles from patients with recessive NLRP7 mutations and the important relationship between NLRP7 defects in the oocyte and p57 expression that appear to be the main contributor to the molar phenotype regardless of the zygote genotype | 32055942 |
| 2020-06-06 12:23:00 | NLRP7 inflammasome is abundantly expressed by trophoblast cells. It is regulated by a key parameter of placental development, hypoxia. It controls trophoblast proliferation, migration, and invasion and exhibits anti-apoptotic role. NLRP7 machinery is deregulated in fetal growth restriction pregnancies. | 30617930 |
| 2020-04-18 12:27:00 | NLRP7 is involved in polarization of decidual macrophages. | 31795138 |
| Type | IDs |
|---|---|
| Synonymous | CLR19.4, HYDM, NALP7, NOD12, PAN7, PYPAF3 |
| Gene |
UniProtKB-ID:
NALP7_HUMAN
UniprotKB:
Q8WX94
UniParc:
UPI0000351D6A,
UPI0000046432,
UPI000174C6C4
EMBL:
AY154462,
AC011476,
AF464765,
BC109125,
BK001113
Ensembl:
ENSG00000277786,
ENSG00000277776,
ENSG00000274174,
ENSG00000277179,
ENSG00000275483,
ENSG00000277071,
ENSG00000167634,
ENSG00000276804,
ENSG00000274571
KO:
hsa:199713
|
| Nucleutide sequences |
EMBL-CDS:
AAL69963.1,
AAO18158.1,
DAA01246.1,
AAI09126.1
Ensembl_TRS:
ENST00000620820,
ENST00000620183,
ENST00000588756,
ENST00000622199,
ENST00000328092,
ENST00000610790,
ENST00000592784,
ENST00000590030,
ENST00000610853,
ENST00000618995,
ENST00000618672,
ENST00000613233,
ENST00000615699,
ENST00000621238,
ENST00000618740,
ENST00000610981,
ENST00000340844,
ENST00000614879,
ENST00000618261,
ENST00000615426,
ENST00000610424,
ENST00000618343,
ENST00000611597,
ENST00000621584
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000482194,
ENSP00000467123,
ENSP00000478890,
ENSP00000481809,
ENSP00000479541,
ENSP00000478726,
ENSP00000483203,
ENSP00000484808,
ENSP00000480449,
ENSP00000479459,
ENSP00000484426,
ENSP00000484444,
ENSP00000483353,
ENSP00000329568,
ENSP00000481452,
ENSP00000339491,
ENSP00000481395,
ENSP00000468706,
ENSP00000481117,
ENSP00000480226,
ENSP00000465520,
ENSP00000480034,
ENSP00000482887,
ENSP00000482551
RefSeq:
NP_001120727.1,
XP_006723138.1,
XP_006723139.1,
XP_011524901.1,
NP_631915.2,
XP_011524898.1,
NP_996611.2,
XP_011524903.1
|
| Others |
UniRef100:
UniRef100_Q8WX94
UniRef90:
UniRef90_Q8WX94
UniRef50:
UniRef50_Q9NX02
UniGene:
Hs.351118
CCDS:
CCDS46183.1,
CCDS12912.1,
CCDS33109.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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||||
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