| Type | Description |
|---|---|
| Definition | DAN domain BMP antagonist family member 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:02:00 | Generation of a gene-corrected human induced pluripotent stem cell line derived from a patient with laterality defects and congenital heart anomalies with a c.455G > A alteration in DAND5. | 31869685 |
| 2019-11-30 12:03:00 | Coco may be a player in the bone morphogenetic protein dysregulation and the tissue repair failure in multiple sclerosis | 30685069 |
| 2017-12-16 10:39:00 | High DAND5 expression is associated with tumor growth and angiogenesis in breast cancer. | 26908452 |
| 2017-08-05 10:12:00 | In this work, we report two patients with a DAND5 heterozygous non-synonymous variant (c.455G > A) in the functional domain of the DAND5 protein (p.R152H), a master regulator of Nodal signaling. Patient 1 presents left isomerism, ventricular septal defect with overriding aorta and pulmonary atresia, while patient 2 presents ventricular septal defect with overriding aorta, right ventricular hypertrophy | 28738792 |
| 2012-11-03 11:10:00 | A gain-of-function cDNA screen reveals that Coco, a secreted antagonist of TGF-beta ligands, induces dormant breast cancer cells to undergo reactivation in the lung. | 22901808 |
| Type | IDs |
|---|---|
| Synonymous | CER2, CERL2, CKTSF1B3, COCO, CRL2, DANTE, GREM3, SP1 |
| Gene |
UniProtKB-ID:
DAND5_HUMAN
UniprotKB:
Q8N907
UniParc:
UPI000007258A
EMBL:
AB070695,
BC113476,
BC101800,
AK095926
Ensembl:
ENSG00000179284
KO:
hsa:199699
|
| Nucleutide sequences |
EMBL-CDS:
BAC82440.1,
AAI01801.1,
BAC04651.1,
AAI13477.1
Ensembl_TRS:
ENST00000317060
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000323155
RefSeq:
NP_689867.1
|
| Others |
UniRef100:
UniRef100_Q8N907
UniRef90:
UniRef90_Q8N907
UniRef50:
UniRef50_Q76LW6
UniGene:
Hs.331981
CCDS:
CCDS12291.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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