| Type | Description |
|---|---|
| Definition | serpin family B member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:47:00 | A striking decrease in the expression of SERPINB1 gene, which encodes a critical component of neutrophil survival, was detected in Cohen syndrome neutrophils. | 30843084 |
| 2020-01-11 10:21:00 | Analysis of The Cancer Genome Atlas and pyrosequencing demonstrate hypermethylation of the SERPINB1 promoter in prostate cancer compared with normal tissue, and the extent of promoter methylation negatively correlates with SERPINB1 mRNA expression. | 30610107 |
| 2019-10-12 10:57:00 | This study demonstrated that female-specific role for SERPINB1 in amyloidosis. | 29967939 |
| 2019-05-04 10:56:00 | Results indicate that serpin family B member 1 (SERPINB1) acts as a vital gatekeeper of inflammation by restraining neutrophil serine proteases and inflammatory caspases in a genetically and functionally separable manner. | 30692621 |
| 2018-06-30 11:27:00 | The expression of SERPINB1 was approximately 2-fold higher in apical periodontitis. SERPINB1 expression was noted in neutrophils and epithelial cells. | 28673495 |
| Type | IDs |
|---|---|
| Synonymous | EI, ELANH2, HEL-S-27, HEL57, LEI, M/NEI, MNEI, PI-2, PI2 |
| Gene |
UniProtKB-ID:
ILEU_HUMAN,
V9HWH1_HUMAN
UniprotKB:
P30740,
V9HWH1
UniParc:
UPI00017A79D3,
UPI000012D514
EMBL:
GQ472232,
BC009015,
CH471087,
AF053630,
AK298044,
AK291327,
AL139092,
AK223370,
M93056,
EU794624,
BT006928
Ensembl:
ENSG00000021355
KO:
hsa:1992
|
| Nucleutide sequences |
EMBL-CDS:
BAF84016.1,
AAH09015.1,
AAC31394.1,
BAG60342.1,
AAP35574.1,
BAD97090.1,
EAW55090.1,
EAW55089.1,
ACV87207.1,
ACJ13678.1
Gene_ORFName:
hCG_1641505
Ensembl_TRS:
ENST00000380739
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000370115
RefSeq:
XP_011512635.1,
XP_011512636.1,
NP_109591.1,
XP_011512637.1
|
| Others |
UniRef100:
UniRef100_P30740
UniRef90:
UniRef90_P30740
UniRef50:
UniRef50_P30740
UniGene:
Hs.381167
CCDS:
CCDS4477.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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