| Type | Description |
|---|---|
| Definition | rod outer segment membrane protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 13:10:00 | Experiments evaluating Prph2 trafficking show that Rom1 is a key determinant of whether Prph2 complexes utilize conventional versus unconventional (Golgi bypass) secretory pathways to reach the OS. | 30307502 |
| 2017-09-16 13:23:00 | ablation of Rom1 results in the conversion of an MD/PD phenotype characterized by cone functional defects and the formation of abnormal Prph2/Rom1 complexes to an RP phenotype characterized by rod-dominant functional defects and reductions in total Prph2 protein. Thus one method by which ROM1 may act as a disease modifier is by contributing to the large variability in PRPH2-associated disease phenotype | 28053051 |
| 2012-04-14 10:49:00 | ROM1 overexpression leads to negative effects on cone outer segments ultrastructure and function. | 22183387 |
| 2010-05-31 11:24:00 | The results suggested that Trp182Arg mutant Rom1 causes a decrease in the levels of wild-type Prph2 and Rom1. | 20300562 |
| Type | IDs |
|---|---|
| Synonymous | M101156, Rgsc1156, Rom-1, Rosp1, Tspan23 |
| Gene |
UniProtKB-ID:
ROM1_MOUSE,
Q3UZZ7_MOUSE
UniprotKB:
P32958,
Q3UZZ7
UniParc:
UPI00000014FD,
UPI00005AB9A8
EMBL:
AK133529,
BC014827,
M96760
Ensembl:
ENSMUSG00000071648
KO:
mmu:19881
|
| Nucleutide sequences |
EMBL-CDS:
AAH14827.1,
AAA40063.1,
BAE21708.1
Ensembl_TRS:
ENSMUST00000096242
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000093961
RefSeq:
NP_033099.3
|
| Others |
UniRef100:
UniRef100_Q3UZZ7,
UniRef100_P32958
UniRef90:
UniRef90_P32958
UniRef50:
UniRef50_P32958
UniGene:
Mm.426094
CCDS:
CCDS29559.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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