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19879 Slc22a8

19879

Slc22a8

solute carrier family 22 (organic anion transporter), member 8

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 22 (organic anion transporter), member 8

研究结论

Date Results Publications
2020-10-24 14:03:00 Unique metabolite preferences of the drug transporters OAT1 and OAT3 analyzed by machine learning. 31896576
2019-07-13 11:24:00 OAT3 increases the glucosuric effect of empagliflozin, which may relate to the partial overlap of its localization with SGLT2 and thus OAT3-mediated tubular secretion of empagliflozin in the early proximal tubule. 29412698
2018-08-18 12:05:00 vitamin D-deficiency resulted in down-regulation of liver Cyp7a1 and renal Oat3, conditions that are alleviated upon replenishment of cholecalciferol. 29243851
2018-06-23 10:37:00 OCT2-independent pathway of cisplatin-induced renal injury that is mediated by the organic anion transporters OAT1 and OAT3, is reported. 28689374
2017-10-14 12:59:00 OAT1 plays a greater role in kidney proximal tubule metabolism and OAT3 appears relatively more important in systemic metabolism, modulating levels of metabolites flowing through intestine, liver, and kidney 28765282

名称对应

Type IDs
Synonymous Oat3, Roct
Gene
UniProtKB-ID: S22A8_MOUSE
UniprotKB: O88909
UniParc: UPI0000021184
EMBL: AB079895, AK157891, AK044336, BC014762, AF078869, AK031962
Ensembl: ENSMUSG00000063796
KO: mmu:19879
Nucleutide sequences
EMBL-CDS: BAC53618.1, AAH14762.1, BAC31873.1, BAC27624.1, AAC61265.1, BAE34249.1
Ensembl_TRS: ENSMUST00000170817, ENSMUST00000010251
Protein sequencees
Ensembl_PRO: ENSMUSP00000010251, ENSMUSP00000131045
RefSeq: NP_001158106.1, NP_112471.3, XP_036017362.1, XP_011245473.1, XP_036017363.1, NP_001158107.1, XP_030106657.1
Others
UniRef100: UniRef100_O88909
UniRef90: UniRef90_O88909
UniRef50: UniRef50_Q4U2R8-4
UniGene: Mm.285294
CCDS: CCDS29537.1

全选

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