| Type | Description |
|---|---|
| Definition | roundabout guidance receptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:03:00 | SLIT2/ROBO1-signaling inhibits macropinocytosis by opposing cortical cytoskeletal remodeling. | 32807784 |
| 2020-02-15 10:54:00 | Here, the report that mammalian ROBO1 and ROBO2 are not uniformly inhibited precrossing and are instead subject to additional temporal control via alternative splicing at a conserved microexon. Postcrossing, the ROBO1 and ROBO2 isoforms are disinhibited to prevent midline reentry and to guide postcrossing commissural axons to distinct mediolateral positions. | 31392959 |
| 2019-08-17 10:51:00 | Compared with proestrus ovaries, the expression levels of Slit2 and Robo1 mRNA in the ovaries during diestrus were significantly up-regulated. The mRNA expression levels of Slit2 and Robo1 in late-phase corpus luteum were significantly increased when compared with pregnant corpus luteum. | 31008488 |
| 2019-06-22 12:31:00 | Study concludes that Robo1 and Robo2 have redundant functions to guide multiple aspects of the complex cell migration of the facial nucleus, as well as regulating axon trajectories and suppressing formation of ectopic axons. | 30685539 |
| 2019-01-05 11:32:00 | In PDAC patients, ROBO2 expression is overall low while ROBO1 is variably expressed in epithelium and high in stroma. ROBO2low;ROBO1high patients present the poorest survival. | 30504844 |
| Type | IDs |
|---|---|
| Synonymous | AW494633, AW742721, DUTT1, Gm310 |
| Gene |
UniProtKB-ID:
ROBO1_MOUSE,
G5E843_MOUSE,
Q3UXH3_MOUSE,
Q3UQ03_MOUSE
UniprotKB:
O89026,
G5E843,
Q3UXH3,
Q3UQ03
UniParc:
UPI0000029797,
UPI00005ABBB0,
UPI00005AC19B,
UPI0000354FA7
EMBL:
AC154782,
AC121890,
AC122016,
AC124726,
AC134431,
AC164551,
AK143001,
AK135605,
Y17793
Ensembl:
ENSMUSG00000022883
KO:
mmu:19876
|
| Nucleutide sequences |
EMBL-CDS:
CAA76850.1,
BAE22590.1,
BAE25241.1
Ensembl_TRS:
ENSMUST00000023600
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023600
RefSeq:
XP_030104865.1,
XP_006523024.1,
NP_062286.2,
XP_006523021.1,
XP_036015712.1,
XP_006523027.1,
XP_017172382.1,
XP_006523023.1,
XP_006523020.1,
XP_036015713.1,
XP_006523026.1,
XP_006523025.1,
XP_006523028.1,
XP_036015711.1,
XP_017172383.1,
XP_030104863.1
|
| Others |
UniRef100:
UniRef100_G5E843,
UniRef100_O89026,
UniRef100_A0A6P7QIA5,
UniRef100_Q3UXH3
UniRef90:
UniRef90_O89026,
UniRef90_A0A3Q0D970
UniRef50:
UniRef50_Q9Y6N7
UniGene:
Mm.310772
CCDS:
CCDS37376.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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