| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 5A |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:17:00 | Hypusination of Eif5a regulates cytoplasmic TDP-43 aggregation and accumulation in a stress-induced cellular model. | 32882370 |
| 2021-04-17 13:12:00 | Inhibition of Eukaryotic Translation Initiation Factor 5A (eIF5A) Hypusination Suppress p53 Translation and Alters the Association of eIF5A to the Ribosomes. | 32605139 |
| 2021-04-13 10:09:00 | Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation. | 33303756 |
| 2021-02-20 13:33:00 | Impaired eIF5A function causes a Mendelian disorder that is partially rescued in model systems by spermidine. | 33547280 |
| 2020-12-12 13:30:00 | A translational program that suppresses metabolism to shield the genome. | 33188200 |
| Type | IDs |
|---|---|
| Synonymous | EIF-5A, EIF5A1, eIF5AI |
| Gene |
UniProtKB-ID:
IF5A1_HUMAN
UniprotKB:
P63241
UniParc:
UPI00001B5C0C,
UPI0000006BEE
EMBL:
M23419,
AY129319,
S72024,
U17969,
BC000751,
BC107779,
BC030160,
BC085015,
AY129322,
AY129320,
CH471108,
BC080196,
BC001832,
AK292615,
AY129321
Ensembl:
ENSG00000132507,
ENSG00000288145
KO:
hsa:1984
|
| Nucleutide sequences |
EMBL-CDS:
BAF85304.1,
AAA58453.1,
AAH30160.1,
EAW90222.1,
AAH85015.1,
AAH80196.1,
AAH00751.1,
AAI07780.1,
AAN17514.1,
EAW90221.1,
EAW90219.1,
AAD14095.1,
AAH01832.1,
EAW90220.1,
AAA86989.1,
AAN17516.1,
AAN17515.1,
AAN17518.1
Ensembl_TRS:
ENST00000673210,
ENST00000336452,
ENST00000673304,
ENST00000419711,
ENST00000576930,
ENST00000672765,
ENST00000573542,
ENST00000673099,
ENST00000336458,
ENST00000673259,
ENST00000672755,
ENST00000416016,
ENST00000571955,
ENST00000672250
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000396073,
ENSP00000459611,
ENSP00000499855,
ENSP00000336776,
ENSP00000500624,
ENSP00000500414,
ENSP00000459196,
ENSP00000458269,
ENSP00000499995,
ENSP00000500669,
ENSP00000390677,
ENSP00000336702,
ENSP00000500847,
ENSP00000500717
RefSeq:
XP_024306401.1,
XP_024306399.1,
NP_001137233.1,
NP_001357349.1,
XP_016879790.1,
XP_011522012.1,
NP_001357350.1,
XP_024306400.1,
NP_001137232.1,
NP_001137234.1,
NP_001961.1,
XP_011522015.1,
XP_024306398.1,
XP_011522013.1,
XP_011522014.1
|
| Others |
UniRef100:
UniRef100_P63241
UniRef90:
UniRef90_P63241
UniRef50:
UniRef50_P63241
UniGene:
Hs.534314
CCDS:
CCDS45601.1,
CCDS11099.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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