| Type | Description |
|---|---|
| Definition | ring finger protein 4 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-10 10:30:00 | These findings suggest that the UBC9/PML/RNF4 axis plays a critical role as an important SUMO pathway in cardiac fibrosis. Modulating the protein levels of the pathway provides an attractive therapeutic target for the treatment of cardiac fibrosis and heart failure. | 28143738 |
| 2015-01-17 11:54:00 | This paper identifies a nucleosome-targeting motif within the RNF4 RING domain that can bind DNA and thereby enables RNF4 to selectively ubiquitinate nucleosomal histones. | 24714598 |
| 2013-12-14 12:34:00 | fork collapse in Atr-deleted cells is mediated through the combined effects the sumo targeted E3-ubiquitin ligase RNF4 and activation of the AURKA-PLK1 pathway | 24142876 |
| 2013-08-31 10:18:00 | Rnf4 controls protein localization at DNA damage sites by integrating SUMOylation and ubiquitylation events. | 23197296 |
| 2013-03-09 12:15:00 | SUMO interacting motif is dispensable for PML SUMOylation and interaction with RNF4 but is required for efficient PML ubiquitination, recruitment of proteasome components within NBs and proteasome-dependent degradation of PML in response to AsO | 23028697 |
| Type | IDs |
|---|---|
| Synonymous | AU018689, Gtrgeo8, SNURF |
| Gene |
UniProtKB-ID:
RNF4_MOUSE
UniprotKB:
Q9QZS2
UniParc:
UPI00000041E2
EMBL:
AK019171,
AK147057,
U95141,
BC003282,
AK159778,
AK151116,
AF169300,
AK090162,
AK159949,
AK158987
Ensembl:
ENSMUSG00000029110
KO:
mmu:19822
|
| Nucleutide sequences |
EMBL-CDS:
BAB31585.1,
AAC53539.1,
BAE34757.1,
BAE27641.1,
AAF00620.1,
BAE35505.1,
BAE35362.1,
BAC41119.1,
BAE30125.1,
AAH03282.1
Ensembl_TRS:
ENSMUST00000030992,
ENSMUST00000182047,
ENSMUST00000182709
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000138411,
ENSMUSP00000138555,
ENSMUSP00000030992
RefSeq:
NP_001291199.1,
NP_035408.1,
NP_001291198.1
|
| Others |
UniRef100:
UniRef100_Q9QZS2
UniRef90:
UniRef90_O88846
UniRef50:
UniRef50_O88846
UniGene:
Mm.21281
CCDS:
CCDS57336.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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