Type | Description |
---|---|
Definition | ribonuclease H1 |
Date | Results | Publications |
---|---|---|
2017-05-27 10:49:00 | RNase H1 is necessary for the activity of DNA-like ASOs. During liver regeneration, a clone of hepatocytes that expressed RNase H1 developed and partially restored mitochondrial and liver function. | 27131367 |
2015-10-31 11:16:00 | the essential role of RNase H1 in mitochondrial DNA replication is the removal of primers at the origin of replication | 26162680 |
2010-11-06 11:00:00 | translational organization of RNase H1 allows tight control of expression of RNase H1 in mitochondria, where its excess or absence can lead to cell death, without affecting the expression of the nuclear RNase H1 | 20823270 |
2010-01-21 00:00:00 | RNase H1 is involved in generation of mitochondrial DNA | 12667461 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
E9QLN8_MOUSE
UniprotKB:
E9QLN8
UniParc:
UPI00000219A2
EMBL:
AC136986
Ensembl:
ENSMUSG00000020630
|
Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000020959
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020959
RefSeq:
NP_001273794.1,
NP_035405.2
|
Others |
UniRef100:
UniRef100_E9QLN8
UniRef90:
UniRef90_O70338
UniRef50:
UniRef50_O60930
UniGene:
Mm.10152
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
27131367 |
Nucleic Acids Res. Walt F Lima , Heather M Murray , Sagar S Damle , Christopher E Hart , Gene Hung , Cheryl Li De Hoyos , Xue-Hai Liang , Stanley T Crooke |
2016-06-20 | - |
26162680 |
Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication. Proc. Natl. Acad. Sci. U.S.A. J Bradley Holmes , Gokhan Akman , Stuart R Wood , Kiran Sakhuja , Susana M Cerritelli , Chloe Moss , Mark R Bowmaker , Howard T Jacobs , Robert J Crouch , Ian J Holt |
2015-07-28 |
Gt(ROSA)26Sor,
Rnaseh1
|
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
20823270 |
Mol Cell Biol Yutaka Suzuki , J Bradley Holmes , Susana M Cerritelli , Kiran Sakhuja , Michal Minczuk , Ian J Holt , Robert J Crouch |
2010-11-01 | - |
19228196 |
Ribonuclease H: the enzymes in eukaryotes. FEBS J Susana M Cerritelli , Robert J Crouch |
2009-03-01 | - |
18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
18614015 |
A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha |
2008-07-11 |
Acacb,
Hscb,
Gadd45gip1,
Lars2,
Acad11,
Chchd10,
Nt5dc3,
Slc25a41,
Nt5m,
Cyp27a1,
Acly,
Ndufb11,
Gldc,
Rexo2,
Rars,
Aldh6a1,
Slc25a47,
Rdh14,
Ppif,
Ldhal6b,
Me2,
Glyat,
Slc25a45,
Acaca,
Nt5c3,
Mrpl10,
Mrpl41,
Mrpl30,
Aldh1l1,
Mthfs,
Shmt2,
Atic,
Mthfd1,
Mat2b,
Fam210a,
Gpt2,
Lyrm2,
Rdh13,
Mtrf1l,
Atad3a,
Rars2,
Sccpdh,
Me3,
Maob,
Dut,
Cyp11b1,
Fdps,
Akr7a5,
Msra,
Krt5,
Cox6b1,
Qdpr,
Acat1,
Acat2,
Aldh7a1,
Pcca,
Etfb,
Etfa,
Nudt19,
Acadl,
Acadm,
Acadvl,
Acaa1a,
Acads,
Aco1,
Aco2,
Prosc,
Afg3l1,
Adsl,
Agxt,
Ak2,
Ak4,
Akap1,
Alas1,
Alas2,
Abcd1,
Aldh2,
Aldh3a2,
Gfer,
Acsm1,
Slc25a4,
Slc25a5,
Prdx3,
Prdx6,
Mrps2,
Arg2,
Rhoa,
Atp5a1,
Atp5b,
Atp5c1,
Atp5f1,
Atp5g1,
Atp5j,
Atp5k,
Atpif1,
Auh,
Akr1b7,
Bad,
Bak1
|
17015433 |
Genes Dev. Alexei V Evsikov , Joel H Graber , J Michael Brockman , Ales Hampl , Andrea E Holbrook , Priyam Singh , John J Eppig , Davor Solter , Barbara B Knowles |
2006-10-01 |
Oog3,
Gm10637,
Cphx2,
Gm10436,
Gm15501,
Gm3139,
Gm3143,
Gm3259,
Gm3286,
Gm4566,
Gm14635,
Gm11238,
Gm12130,
Gm38425,
Oas1d,
Nfxl1,
A730082K24Rik,
Mtus1,
Dcun1d2,
Lrrc49,
Ndufb11,
Golm1,
Chmp7,
Cmc4,
AU021063,
Cops8,
Rnf20,
2610305D13Rik,
Serpinc1,
Bmp15,
Birc6,
Aspm,
Cnih1,
Daxx,
Ebp,
Mark2,
Epc1,
Fgfr2,
Fkbp2,
Fkbp8,
Gart,
Gclm,
Gpr19,
Trip12,
Hnrnpc,
Eif2ak1,
Ica1,
Itpr1,
Lama5,
Lamc2,
Glcci1,
Mfap2,
Mtf1,
Mthfd2,
Usp34,
Myo5b,
Nf2,
Nfyc,
Nudc,
Odf2,
Omt2a,
Slc25a15,
Igbp1,
Per3,
Pex7,
Abcb1b,
Plaa,
Plat,
Ppp5c,
Proc,
Ptprr,
Oog1,
Gm13103,
Klf11,
Rdx,
Rnaseh1,
Trim30a,
Siah1b,
Bptf,
Spin1,
Esrp1,
Aurkc,
Fanci,
Surf4,
Suv39h1,
Pdlim2,
Tcl1,
Tdrd5,
Mcu,
Os9,
Clint1,
Heatr6,
Gm11545,
Tex264,
Cirh1a,
Eif4e1b,
Top1,
Ttk,
Ubc
|
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