| Type | Description |
|---|---|
| Definition | Ras-like without CAAX 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 10:29:00 | RIT1 is widely expressed in the murine retina, including both Muller glia and RGCs. While genetic deletion of RIT1 does not result in gross retinal abnormalities | 29843527 |
| 2019-08-24 12:09:00 | we generated a novel knock-in Rit1A57G/+ mouse that presents features that are relevant to NS patients with a Rit1 mutation, including craniofacial dysmorphia, short stature, and cardiac hypertrophy. | 30898653 |
| 2017-07-08 10:46:00 | In adult hippocampal neuronal precursor cells, RIT1 controls an Akt-dependent signaling cascade, resulting in the stabilization and transcriptional activation of phosphorylated Sox2. This study supports a role for RIT1 in relaying niche-derived signals to neural/stem progenitor cells to control transcription of genes involved in self-renewal and differentiation | 28007959 |
| 2013-02-23 11:19:00 | the Rit-p38-MSK1/2 signaling pathway may have an important role in the stress-dependent regulation of CREB-dependent gene expression. | 23038261 |
| 2012-10-27 10:12:00 | these data identify a new and unexpected role for Rit in injury-induced neurogenesis, functioning as a selective survival mechanism for immature hippocampal neurons within the subgranular zone of the dentate gyrus following TBI. | 22815504 |
| Type | IDs |
|---|---|
| Synonymous | RIBB, ROC1, Rit |
| Gene |
UniProtKB-ID:
RIT1_MOUSE,
A0A1S6GWG2_MOUSE,
E9Q672_MOUSE
UniprotKB:
P70426,
A0A1S6GWG2,
E9Q672
UniParc:
UPI0001AFF953,
UPI0003D727AC,
UPI0000022DA1
EMBL:
AC134246,
U71205,
KY499673,
AK005357,
BC012694,
AK014126
Ensembl:
ENSMUSG00000028057
KO:
mmu:19769
|
| Nucleutide sequences |
EMBL-CDS:
AAH12694.1,
BAB29168.1,
AAB42215.1,
BAB23972.1,
AQS27594.1
Ensembl_TRS:
ENSMUST00000029692,
ENSMUST00000172252
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029692,
ENSMUSP00000130464
RefSeq:
NP_001156782.1,
XP_006501221.1,
XP_030108338.1,
XP_006501223.1,
NP_033095.1,
XP_036018857.1
|
| Others |
UniRef100:
UniRef100_A0A1S6GWG2,
UniRef100_P70426
UniRef90:
UniRef90_P70426
UniRef50:
UniRef50_P70426
UniGene:
Mm.4009
CCDS:
CCDS17484.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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