| Type | Description |
|---|---|
| Definition | Ras homolog enriched in brain |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:24:00 | RHEB gene therapy maintains the chondrogenic characteristics and protects cartilage tissue from degenerative damage during experimental murine osteoarthritis. | 31229684 |
| 2020-07-18 11:44:00 | Our study demonstrates that Rheb, by selectively modulating thermogenic gene expression in brown and beige adipose tissues, plays an important role in regulating energy homeostasis. | 31220300 |
| 2020-05-09 12:12:00 | Rheb1 deficiency led to a progressive enlargement of the hematopoietic stem cell population and an eventual excessive myeloproliferation in vivo, including an overproduction of peripheral neutrophils and an excessive expansion of extramedullary hematopoiesis | 30262562 |
| 2019-10-26 11:31:00 | Compensatory cardiac hypertrophy activates ER stress and ATF6, which induces RHEB and activates mTORC1. Thus, ATF6 is a previously unrecognized link between growth stimuli and mTORC1-mediated cardiac growth. | 30582446 |
| 2019-08-10 12:19:00 | These results suggest that inter-organelle communication between the Golgi and lysosome is important for mTORC1 regulation and the Golgi-localized Rheb may activate mTORC1 at Golgi-lysosome contact site. | 29222112 |
| Type | IDs |
|---|---|
| Synonymous | Rheb1 |
| Gene |
UniProtKB-ID:
RHEB_MOUSE,
Q540E6_MOUSE
UniprotKB:
Q921J2,
Q540E6
UniParc:
UPI0000006462
EMBL:
BC012273,
AK151213,
AY197373
Ensembl:
ENSMUSG00000028945
KO:
mmu:19744
|
| Nucleutide sequences |
EMBL-CDS:
AAH12273.1,
BAE30208.1,
AAO43226.1
Ensembl_TRS:
ENSMUST00000030787
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030787
RefSeq:
NP_444305.2
|
| Others |
UniRef100:
UniRef100_Q921J2
UniRef90:
UniRef90_Q921J2
UniRef50:
UniRef50_Q15382
UniGene:
Mm.319175
CCDS:
CCDS39032.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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