| Type | Description |
|---|---|
| Definition | regulator of G-protein signaling 9 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-16 10:39:00 | Ablation of RGS9-2 in cultured striatal neurons reduced calcium influx thru NMDARs. Mice lacking RGS9-2 displayed behavioral hypersensitivity to NMDAR blockade.These changes were selective to D2-medium spiny neurons, increasing the frequency of mEPSC and inhibiting paired-pulse ratio.mediated by the NMDAR-dependent inhibition of D2-MSN retrograde endocannabinoid signaling to CB1 receptor on presynaptic terminals. | 30006367 |
| 2019-08-10 10:28:00 | The authors show that genetic depletion of RGS9-2 mimics the D2 receptor loss of DYT1 dystonia striatum, whereas RGS9-2 overexpression rescues both receptor levels and electrophysiological responses in Dyt1 striatal neurons. | 30552094 |
| 2016-08-06 10:15:00 | Association with the plasma membrane is sufficient for potentiating catalytic activity of RGS7 and RGS9-2 proteins. | 26811338 |
| 2016-01-16 11:43:00 | Data show that the regulator of G-protein signaling 9-2 (RGS9-2) in the nucleus accumbens (NAc) affects the expression of many genes known to be involved in nociception, analgesia, and antidepressant drug actions. | 26305935 |
| 2015-08-08 10:35:00 | role in sensory and mood related symptoms of neuropathic pain | 25150149 |
| Type | IDs |
|---|---|
| Synonymous | RGS9-1, Rgs9-2 |
| Gene |
UniProtKB-ID:
RGS9_MOUSE,
Q3UUR0_MOUSE
UniprotKB:
O54828,
Q3UUR0
UniParc:
UPI0000192B5D,
UPI000059DDA6
EMBL:
AK138159,
AL604043,
AF011358,
CH466558,
AF125046,
BC129899
Ensembl:
ENSMUSG00000020599
KO:
mmu:19739
|
| Nucleutide sequences |
EMBL-CDS:
AAI29900.1,
AAC99481.1,
EDL34351.1,
AAD20014.1,
BAE23565.1
Ensembl_TRS:
ENSMUST00000020920,
ENSMUST00000106706
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020920,
ENSMUSP00000102317
RefSeq:
XP_011247130.2,
NP_035398.2,
NP_001159406.1
|
| Others |
UniRef100:
UniRef100_O54828,
UniRef100_Q3UUR0
UniRef90:
UniRef90_P49805,
UniRef90_O75916-3
UniRef50:
UniRef50_O75916-3,
UniRef50_O75916-5
UniGene:
Mm.38548
CCDS:
CCDS48969.1,
CCDS25576.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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