| Type | Description |
|---|---|
| Definition | NLR family CARD domain containing 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 10:21:00 | Down-regulated expression of NLRC3 may play an important role in cancer progression and prognosis of HCC by acting as a tumor suppressor. | 30081150 |
| 2019-07-20 10:03:00 | expression of NLRC3 was significantly associated with CD8+ T cells infiltration | 31303617 |
| 2018-04-21 11:36:00 | NLRC3 promoted K48-linked polyubiquitination and degradation of interleukin-1 receptor-associated kinase 1 (IRAK1). | 28731142 |
| 2017-09-30 11:35:00 | The NLRC3 interferes with the assembly and activity of the NALP3 inflammasome complex by competing with ASC for pro-caspase-1 binding. | 28584053 |
| 2016-09-17 12:01:00 | The extent of NLRC3 and AIM2 gene reduction was correlated with cancer progression. | 26378020 |
| Type | IDs |
|---|---|
| Synonymous | CLR16.2, NOD3 |
| Gene |
UniProtKB-ID:
NLRC3_HUMAN,
C3VPR7_HUMAN,
Q8NF06_HUMAN
UniprotKB:
Q7RTR2,
C3VPR7,
Q8NF06
UniParc:
UPI00000730C8,
UPI00001C1FB3,
UPI00015887D4,
UPI00004CE17D,
UPI00015887D3
EMBL:
AF501292,
FJ889357,
AK090431,
CH471112,
AK090476,
AY601811,
AF501291,
AK074109,
BK001112
Ensembl:
ENSG00000167984
KO:
hsa:197358
|
| Nucleutide sequences |
EMBL-CDS:
DAA01245.1,
BAB84935.1,
AAM22459.1,
AAM22460.1,
AAT48367.1,
BAC03412.1,
EAW85350.1,
ACP40993.1,
BAC03457.1
Gene_ORFName:
hCG_2036791
Ensembl_TRS:
ENST00000359128,
ENST00000615877
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000352039,
ENSP00000482989
RefSeq:
XP_016878523.1,
XP_016878517.1,
XP_016878520.1,
XP_016878527.1,
XP_016878524.1,
NP_849172.2,
XP_016878525.1,
XP_016878526.1,
XP_016878528.1,
XP_016878516.1,
XP_016878518.1,
XP_016878522.1,
XP_016878519.1
|
| Others |
UniRef100:
UniRef100_Q7RTR2,
UniRef100_Q8NF06
UniRef90:
UniRef90_Q7RTR2,
UniRef90_Q8NF06
UniRef50:
UniRef50_Q7RTR2,
UniRef50_Q5DU56-2
UniGene:
Hs.592091
CCDS:
CCDS73817.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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