| Type | Description |
|---|---|
| Definition | essential meiotic structure-specific endonuclease subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2016-11-05 11:23:00 | Avoiding damage formation through invalidation of Mus81-Eme2 and Mre11, or preventing damage signaling by turning off the ATM pathway, suppresses the replication phenotypes of Chk1-deficient cells. | 26804904 |
| 2015-04-25 11:36:00 | Results define distinct and temporal roles for MUS81-EME1 and MUS81-EME2 in the maintenance of genome stability. | 24813886 |
| 2014-07-19 10:46:00 | The presence of a 5' phosphate terminus at nicks and gaps rendered DNA significantly less susceptible to the cleavage by MUS81-EME2 than its absence. | 24692662 |
| 2014-06-28 13:46:00 | The results indicate that MUS81-EME2 is a more active endonuclease than MUS81-EME1 and exhibits broader substrate specificity. | 24371268 |
| Type | IDs |
|---|---|
| Synonymous | SLX2B, gs125 |
| Gene |
UniProtKB-ID:
EME2_HUMAN
UniprotKB:
A4GXA9
UniParc:
UPI00001C1FB2,
UPI0000F57C10
EMBL:
AK074080,
AE006639,
EF452422
Ensembl:
ENSG00000197774
KO:
hsa:197342
|
| Nucleutide sequences |
EMBL-CDS:
BAB84906.2,
AAK61292.1,
ABO21766.1
Ensembl_TRS:
ENST00000568449
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000457353
RefSeq:
XP_016878515.1,
XP_016878514.1,
NP_001244299.1
|
| Others |
UniRef100:
UniRef100_A4GXA9
UniRef90:
UniRef90_A4GXA9
UniRef50:
UniRef50_A4GXA9
UniGene:
Hs.7247
CCDS:
CCDS58404.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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